Vitamin C—sources, physiological role, kinetics, deficiency, use, toxicity, and determination

M Doseděl, E Jirkovský, K Macáková, LK Krčmová… - Nutrients, 2021 - mdpi.com
Vitamin C (L-ascorbic acid) has been known as an antioxidant for most people. However, its
physiological role is much larger and encompasses very different processes ranging from …

The pharmacokinetics of vitamin C

J Lykkesfeldt, P Tveden-Nyborg - Nutrients, 2019 - mdpi.com
The pharmacokinetics of vitamin C (vitC) is indeed complex. Regulated primarily by a family
of saturable sodium dependent vitC transporters (SVCTs), the absorption and elimination …

[HTML][HTML] B vitamins and the brain: mechanisms, dose and efficacy—a review

DO Kennedy - Nutrients, 2016 - mdpi.com
The B-vitamins comprise a group of eight water soluble vitamins that perform essential,
closely inter-related roles in cellular functioning, acting as co-enzymes in a vast array of …

Ascorbic acid: chemistry, biology and the treatment of cancer

J Du, JJ Cullen, GR Buettner - … et Biophysica Acta (BBA)-Reviews on …, 2012 - Elsevier
Since the discovery of vitamin C, the number of its known biological functions is continually
expanding. Both the names ascorbic acid and vitamin C reflect its antiscorbutic properties …

Vitamin C and immune cell function in inflammation and cancer

A Ang, JM Pullar, MJ Currie… - Biochemical Society …, 2018 - portlandpress.com
Vitamin C (ascorbate) is maintained at high levels in most immune cells and can affect many
aspects of the immune response. Intracellular levels generally respond to variations in …

Small intestinal microbial dysbiosis underlies symptoms associated with functional gastrointestinal disorders

GB Saffouri, RR Shields-Cutler, J Chen, Y Yang… - Nature …, 2019 - nature.com
Small intestinal bacterial overgrowth (SIBO) has been implicated in symptoms associated
with functional gastrointestinal disorders (FGIDs), though mechanisms remain poorly …

Oxidative stress and metabolic perturbations in wooden breast disorder in chickens

B Abasht, MF Mutryn, RD Michalek, WR Lee - PloS one, 2016 - journals.plos.org
This study was conducted to characterize metabolic features of the breast muscle (pectoralis
major) in chickens affected with the Wooden Breast myopathy. Live birds from two purebred …

Plant L‐ascorbic acid: chemistry, function, metabolism, bioavailability and effects of processing

MW Davey, MV Montagu, D Inze… - Journal of the …, 2000 - Wiley Online Library
Humans are unable to synthesise l‐ascorbic acid (L‐AA, ascorbate, vitamin C), and are thus
entirely dependent upon dietary sources to meet needs. In both plant and animal …

Ascorbic acid: much more than just an antioxidant

O Arrigoni, MC De Tullio - Biochimica et Biophysica Acta (BBA)-General …, 2002 - Elsevier
Vitamin C (ascorbic acid (AA)) is very popular for its antioxidant properties. Consequently,
many other important aspects of this multifaceted molecule are often underestimated or even …

Global reconstruction of the human metabolic network based on genomic and bibliomic data

NC Duarte, SA Becker, N Jamshidi… - Proceedings of the …, 2007 - National Acad Sciences
Metabolism is a vital cellular process, and its malfunction is a major contributor to human
disease. Metabolic networks are complex and highly interconnected, and thus systems-level …