About 10% of women of reproductive age are unable to conceive or carry a pregnancy to
term. Female factors alone account for at least 35% of all infertility cases and comprise a …

Gestational trophoblastic disease (GTD) is subclassified into hydatidiform mole (HM),
gestational trophoblastic tumours (GTT) and non-neoplastic trophoblastic lesions. HM …

BACKGROUND Human reproductive issues affecting fetal and maternal health are caused
by numerous exogenous and endogenous factors, of which the latter undoubtedly include …

Hydatidiform moles are rare and thus most pathologists and geneticists have little
experience with their diagnosis. It is important to promptly and correctly identify hydatidiform …

Androgenetic complete hydatidiform moles are human pregnancies with no embryos and
affect 1 in every 1,400 pregnancies. They have mostly androgenetic monospermic genomes …

Maternal effect genes (MEGs) encode factors (eg, RNA) that are present in the oocyte and
required for early embryonic development. Hence, while these genes and gene products are …

Background Imprinting disorders are a group of congenital diseases which are
characterized by molecular alterations affecting differentially methylated regions (DMRs). To …

Immunohistochemical analysis of p57 expression and molecular genotyping accurately
subclassify molar specimens into complete hydatidiform mole (CHM) and partial …

Reproductive diseases are a long‐standing problem and have become more common in the
world. Currently, 15% of the world's population suffers from infertility, and half of them are …

Research question What is the genetic cause of sporadic and recurrent pregnancy loss and
does the frequency and nature of chromosomal abnormalities play a role? Types and …