Mechanisms of focal heat destruction of liver tumors

M Nikfarjam, V Muralidharan, C Christophi - Journal of Surgical Research, 2005 - Elsevier
BACKGROUND: Focal heat destruction has emerged as an effective treatment strategy in
selected patients with malignant liver tumors. Radiofrequency ablation, interstitial laser …

Mechanisms for Hsp70 secretion: crossing membranes without a leader

SS Mambula, MA Stevenson, K Ogawa… - Methods, 2007 - Elsevier
Heat shock protein 70 (Hsp70) is released from cells of many types and plays a significant
signaling role, particularly in the inflammatory and immune responses. However, Hsp70 …

Heat shock protein 70 is secreted from tumor cells by a nonclassical pathway involving lysosomal endosomes

SS Mambula, SK Calderwood - The Journal of Immunology, 2006 - journals.aai.org
Heat shock protein (HSP) 70 can be released from tumor cells and stimulate a potent
antitumor immune response. However, HSP70 does not contain a consensus secretory …

The treatment of malignancy by hyperthermia

C Christophi, A Winkworth, V Muralihdaran, P Evans - Surgical oncology, 1998 - Elsevier
The use of hyperthermia for the selective destruction of tumours may be applied by a whole
body, surgical perfusion or interstitial techniques. The main determinant of selectivity is …

Clinical application of hyperthermia combined with anticancer drugs for the treatment of solid tumors

I Takahashi, Y Emi, S Hasuda, Y Kakeji, Y Maehara… - Surgery, 2002 - Elsevier
Background. Hyperthermia is one of the modalities used to treat various forms of
malignancies, including esophageal, stomach, or rectal cancers. Methods. The basic …

Patterns of heat shock protein (HSP70) expression and Kupffer cell activity following thermal ablation of liver and colorectal liver metastases

M Nikfarjam, V Muralidharan, K Su… - International journal …, 2005 - Taylor & Francis
The time course and extent of thermal ablative injury differs in liver compared to tumour
tissue. This may be influenced by differences in the expression of heat shock proteins (HSP) …

[PDF][PDF] Hyperthermia, systemic

RW Rowe-Horwege - Encyclopedia of Medical Devices and …, 2006 - Citeseer
Systemic hyperthermia is deliberate heating of the whole body to achieve an elevated core
temperature for therapeutic purposes. Other terms used are whole-body hyperthermia …

Feasibility of new heating method of hepatic parenchyma using a sintered MgFe2O4 needle under an alternating magnetic field

K Sato, Y Watanabe, A Horiuchi, S Yukumi… - Journal of Surgical …, 2008 - Elsevier
BACKGROUND: Magnetic metal particles such as magnesium ferrite (MgFe2O4) induce
heat energy under an alternating magnetic field that was produced by electric current. We …

热化疗及其在肺癌中的应用

陈敬华, 焦顺昌 - 中国肿瘤临床, 2006 - cjco.cn
随着热疗及热化疗的发展, 热化疗已成为一种新的肿瘤综合治疗模式. 现介绍热化疗的作用机制
与其在肺癌中的临床应用. Abstract: With the development of hyperthermia and …

[引用][C] 肿瘤热化疗生物机制及其临床应用

陈敬华, 焦顺昌 - 中华肿瘤防治杂志, 2006