Accumulating evidence points to the existence of an inflammatory‐metabolic phenotype of
heart failure with a preserved ejection fraction (HFpEF), which is characterized by …

Diabetes promotes the development of both heart failure with a reduced ejection fraction
and heart failure with a preserved ejection fraction through diverse mechanisms, which are …

Epicardial adipose tissue (EAT) is a small but very biologically active ectopic fat depot that
surrounds the heart. Given its rapid metabolism, thermogenic capacity, unique …

Background Epicardial fat tissue (EFT) is the visceral fat distributed along the coronary
arteries between the pericardium and the myocardium. Increases in EFT are closely related …

Coronary CT angiography (CCTA) has evolved into a first-line diagnostic test for the
investigation of chest pain. Despite advances toward standardizing the reporting of CCTA …

Lipolysis of triglyceride-rich lipoproteins by LpL is a central event in lipid metabolism,
releasing fatty acids for uptake by tissues and generating low-density lipoprotein and …

Obesity and diabetes can lead to heart failure with preserved ejection fraction (HFpEF),
potentially because they both cause expansion and inflammation of epicardial adipose …

Both obesity and type 2 diabetes are important risk factors for atrial fibrillation (AF), possibly
because they both cause an expansion of epicardial adipose tissue, which is the source of …

The observation of correlations between obesity and chronic metabolic and cardiovascular
diseases has led to the emergence of strong interests in “adipocyte biology”, in particular in …

Background: Type 2 diabetes is one of the most common chronic disorders worldwide and is
an important cause of cardiovascular disease. Studies investigating the risk of atrial and …