An overview on nucleic-acid G-quadruplex prediction: from rule-based methods to deep neural networks
K Elimelech-Zohar, Y Orenstein - Briefings in Bioinformatics, 2023 - academic.oup.com
Nucleic-acid G-quadruplexes (G4s) play vital roles in many cellular processes. Due to their
importance, researchers have developed experimental assays to measure nucleic-acid G4s …
importance, researchers have developed experimental assays to measure nucleic-acid G4s …
G-quadruplexes from non-coding RNAs
F Li, J Zhou - Journal of Molecular Medicine, 2023 - Springer
Non-coding RNAs (ncRNAs) are significant regulators of gene expression in a wide range of
biological processes, such as transcription, RNA maturation, or translation. ncRNAs …
biological processes, such as transcription, RNA maturation, or translation. ncRNAs …
[HTML][HTML] Development of a highly optimized procedure for the discovery of RNA G-quadruplexes by combining several strategies
RNA G-quadruplexes (rG4s) are non-canonical secondary structures that are formed by the
self-association of guanine quartets and that are stabilized by monovalent cations (eg …
self-association of guanine quartets and that are stabilized by monovalent cations (eg …
ALS-associated FUS mutation reshapes the RNA and protein composition of stress granules
D Mariani, A Setti, F Castagnetti, E Vitiello… - Nucleic Acids …, 2024 - academic.oup.com
Stress granules (SG) are part of a cellular protection mechanism where untranslated
messenger RNAs and RNA-binding proteins are stored upon conditions of cellular stress …
messenger RNAs and RNA-binding proteins are stored upon conditions of cellular stress …
The multivalent G-quadruplex (G4)-ligands MultiTASQs allow for versatile click chemistry-based investigations
FR Sperti, J Mitteaux, J Zell, A Pipier… - RSC Chemical …, 2023 - pubs.rsc.org
Chemical biology hinges on multivalent molecular tools that can specifically interrogate
and/or manipulate cellular circuitries from the inside. The success of many of these …
and/or manipulate cellular circuitries from the inside. The success of many of these …
A G-quadruplex structure in microRNA interferes with messenger RNA recognition and controls gene expression
We identify and characterize an RNA G-quadruplex (rG4) structure motif in the human
microRNA 638 (hsa-miR-638). We investigate the formation and role of this rG4 in vitro and …
microRNA 638 (hsa-miR-638). We investigate the formation and role of this rG4 in vitro and …
A Molecular Orchestration of Plant Translation under Abiotic Stress
AV Suhorukova, DS Sobolev, IG Milovskaya… - Cells, 2023 - mdpi.com
The complexities of translational strategies make this stage of implementing genetic
information one of the most challenging to comprehend and, simultaneously, perhaps the …
information one of the most challenging to comprehend and, simultaneously, perhaps the …
RNA G-quadruplex (rG4) structure detection using RTS and SHALiPE assays
RNA G-quadruplexes (rG4s) are non-canonical RNA secondary structures that were first
reported several decades ago. Latest studies have suggested that they are widespread in …
reported several decades ago. Latest studies have suggested that they are widespread in …
Quadrupia: Derivation of G-quadruplexes for organismal genomes across the tree of life
G-quadruplex DNA structures exhibit a profound influence on essential biological
processes, including transcription, replication, telomere maintenance, and genomic stability …
processes, including transcription, replication, telomere maintenance, and genomic stability …
DHX36 binding induces RNA structurome remolding and regulates RNA abundance via m6A/YTHDF1
RNA structure constitutes a new layer of gene regulatory mechanisms. RNA binding proteins
can modulate RNA secondary structures, thus participating in post-transcriptional regulation …
can modulate RNA secondary structures, thus participating in post-transcriptional regulation …