Opening doors with ultrasound and microbubbles: Beating biological barriers to promote drug delivery
Apart from its clinical use in imaging, ultrasound has been thoroughly investigated as a tool
to enhance drug delivery in a wide variety of applications. Therapeutic ultrasound, as such …
to enhance drug delivery in a wide variety of applications. Therapeutic ultrasound, as such …
Understanding ultrasound induced sonoporation: definitions and underlying mechanisms
I Lentacker, I De Cock, R Deckers, SC De Smedt… - Advanced drug delivery …, 2014 - Elsevier
In the past two decades, research has underlined the potential of ultrasound and
microbubbles to enhance drug delivery. However, there is less consensus on the …
microbubbles to enhance drug delivery. However, there is less consensus on the …
The role of ultrasound-driven microbubble dynamics in drug delivery: from microbubble fundamentals to clinical translation
In the last couple of decades, ultrasound-driven microbubbles have proven excellent
candidates for local drug delivery applications. Besides being useful drug carriers …
candidates for local drug delivery applications. Besides being useful drug carriers …
Ultrasound-mediated tumor imaging and nanotherapy using drug loaded, block copolymer stabilized perfluorocarbon nanoemulsions
Perfluorocarbon nanoemulsions can deliver lipophilic therapeutic agents to solid tumors and
simultaneously provide for monitoring nanocarrier biodistribution via ultrasonography and/or …
simultaneously provide for monitoring nanocarrier biodistribution via ultrasonography and/or …
Ultrasound and microbubble mediated drug delivery: acoustic pressure as determinant for uptake via membrane pores or endocytosis
I De Cock, E Zagato, K Braeckmans, Y Luan… - Journal of controlled …, 2015 - Elsevier
Although promising results are achieved in ultrasound mediated drug delivery, its underlying
biophysical mechanisms remain to be elucidated. Pore formation as well as endocytosis has …
biophysical mechanisms remain to be elucidated. Pore formation as well as endocytosis has …
A concise review on cancer treatment methods and delivery systems
E Bidram, Y Esmaeili, H Ranji-Burachaloo… - Journal of Drug Delivery …, 2019 - Elsevier
The ultimate purpose of current cancer research is to develop a comprehensive treatment for
cancer. Recent studies have shown an increased interest in investigating the capacity of …
cancer. Recent studies have shown an increased interest in investigating the capacity of …
Cardiovascular drug delivery with ultrasound and microbubbles
E Unger, T Porter, J Lindner, P Grayburn - Advanced drug delivery reviews, 2014 - Elsevier
Microbubbles lower the threshold for cavitation of ultrasound and have multiple potential
therapeutic applications in the cardiovascular system. One of the first therapeutic …
therapeutic applications in the cardiovascular system. One of the first therapeutic …
Nanobubbles: a promising efficient tool for therapeutic delivery
R Cavalli, M Soster, M Argenziano - Therapeutic delivery, 2016 - Taylor & Francis
In recent decades ultrasound-guided delivery of drugs loaded on nanocarriers has been the
focus of increasing attention to improve therapeutic treatments. Ultrasound has often been …
focus of increasing attention to improve therapeutic treatments. Ultrasound has often been …
Microbubbles as ultrasound contrast agents for molecular imaging: preparation and application
S Unnikrishnan, AL Klibanov - American journal of …, 2012 - Am Roentgen Ray Soc
OBJECTIVE. The purpose of this review is to describe trends in microbubble application in
molecular imaging. CONCLUSION. Microbubbles are used for contrast ultrasound imaging …
molecular imaging. CONCLUSION. Microbubbles are used for contrast ultrasound imaging …
Current advances in ultrasound-combined nanobubbles for cancer-targeted therapy: a review of the current status and future perspectives
C Su, XJ Ren, F Nie, T Li, W Lv, H Li, Y Zhang - RSC advances, 2021 - pubs.rsc.org
The non-specific distribution, non-selectivity towards cancerous cells, and adverse off-target
side effects of anticancer drugs and other therapeutic molecules lead to their inferior clinical …
side effects of anticancer drugs and other therapeutic molecules lead to their inferior clinical …