The β‐lactams—a large class of diverse compounds—due to their excellent safety profile
and broad antimicrobial spectrum are considered to be the most widely used therapeutic …

Carbapenemases are β-lactamases with versatile hydrolytic capacities. They have the ability
to hydrolyze penicillins, cephalosporins, monobactams, and carbapenems. Bacteria …

Extended‐spectrum β‐lactamases (ESBLs) represent a major threat among resistant
bacterial isolates. The first types described were derivatives of the TEM‐1, TEM‐2 and SHV …

CTX‐M‐type enzymes are a group of class A extended‐spectrum β‐lactamases (ESBLs)
that are rapidly spreading among Enterobacteriaceae worldwide. More that 50 allotypes are …

Carbapenems, such as imipenem and meropenem, are most often used to treat infections
caused by enterobacteria that produce extended-spectrum β-lactamases, and the …

The ongoing global spread and increased prevalence of CTX-M-type extended-spectrum β-
lactamases in Enterobacteriaceae is of great concern. The successful distribution of CTX-M …

Asia is almost certainly a part of the world in which extended‐spectrum β‐lactamases
(ESBLs) have emerged de novo, with some early antimicrobial resistance studies showing …

Gram-negative bacteria, especially Enterobacterales, have emerged as major players in
antimicrobial resistance worldwide. Resistance may affect all major classes of anti-gram …

Objectives To investigate the prevalence of plasmid-mediated fosfomycin resistance
determinants among extended-spectrum β-lactamase (ESBL)-producing Escherichia coli …

Background Due to limited therapeutic options, the spread of extended-spectrum beta-
lactamases (ESBLs) have become a major public health concern. We conducted a …