Clinical metagenomic next-generation sequencing (mNGS), the comprehensive analysis of
microbial and host genetic material (DNA and RNA) in samples from patients, is rapidly …

This review provides a state-of-the-art description of the performance of Sanger cycle
sequencing of the 16S rRNA gene for routine identification of bacteria in the clinical …

Background Pleural effusion is common in routine medical practice and can be due to many
different underlying diseases. Precise differential diagnostic categorization is essential, as …

Bacterial infections are very common and represent one of the most important reasons of
progression of liver failure, development of liver-related complications, and mortality in …

Nucleic Acid Testing (NAT) promises rapid, sensitive and specific diagnosis of infectious,
inherited and genetic disease. The next generation of diagnostic devices will interrogate the …

Genomics and whole genome sequencing (WGS) have the capacity to greatly enhance
knowledge and understanding of infectious diseases and clinical microbiology. The growth …

Bacterial keratitis is a common corneal infection that is treated with topical antimicrobials. By
the time of presentation there may already be severe visual loss from corneal ulceration and …

The laboratory diagnosis of infections is based on pathogen identification and antimicrobial
susceptibility determination. The gold standard of cultivation, isolation and susceptibility …

Rapid and accurate identification of microorganisms, a prerequisite for appropriate patient
care and infection control, is a critical function of any clinical microbiology laboratory. Matrix …

Rising consumption, large-scale production, and widespread distribution have been
accompanied by an increase in the number of Salmonella infections reported to implicate …