Abstract Global Strategy for the Diagnosis, Management, and Prevention of COPD 2018 is a
consensus report published periodically since 2001 by an international panel of health …

α1-antitrypsin deficiency (AATD) is the most common hereditary disorder in adults. It is
associated with an increased risk of developing pulmonary emphysema and liver disease …

This Executive Summary of the Global Strategy for the Diagnosis, Management, and
Prevention of COPD, Global Initiative for Chronic Obstructive Lung Disease (GOLD) 2017 …

Rationale: Single-center randomized controlled trials of the Zephyr endobronchial valve
(EBV) treatment have demonstrated benefit in severe heterogeneous emphysema. This is …

Rationale: Endobronchial valves (EBVs) have been successfully used in patients with
severe heterogeneous emphysema to improve lung physiology. Limited available data …

Obstructive sleep apnea (OSA) is a complex and heterogeneous disorder and the apnea
hypopnea index alone can not capture the diverse spectrum of the condition. Enhanced …

Rationale: This is the first multicenter randomized controlled trial to evaluate the
effectiveness and safety of Zephyr Endobronchial Valve (EBV) in patients with little to no …

Importance Preliminary clinical trials have demonstrated that endobronchial coils compress
emphysematous lung tissue and may improve lung function, exercise tolerance, and …

Alveolar-pleural fistulas causing persistent air leaks (PALs) are associated with prolonged
hospital stays and high morbidity. Prior guidelines recommend surgical repair as the gold …

Das vorliegende Dokument ist eine Neufassung und Aktualisierung der Leitlinie zur
Diagnostik und Therapie von Patienten mit COPD, die die bisherige Version aus dem Jahr …