CD146 is a cell adhesion molecule (CAM) that is primarily expressed at the intercellular
junction of endothelial cells. CD146 was originally identified as a tumor marker for …

Background During the last two decades, over 100 proteomics studies have identified a
variety of potential biomarkers in CSF of Alzheimer's (AD) patients. Although several reviews …

The trafficking of autoreactive leucocytes across the blood–brain barrier endothelium is a
hallmark of multiple sclerosis pathogenesis. Although the blood–brain barrier endothelium …

In multiple sclerosis, encephalitogenic CD4+ lymphocytes require adhesion molecules to
accumulate into central nervous system inflammatory lesions. Using proteomic techniques …

TH17 cells enter tissues to facilitate pathogenic autoimmune responses, including multiple
sclerosis (MS). However, the adhesion molecules involved in the unique migratory capacity …

In this work, we demonstrate an integrated, single-layer, miniature flow cytometry device that
is capable of multi-parametric particle analysis. The device integrates both particle focusing …

Idiopathic pulmonary fibrosis (IPF) is a progressive devastating, yet untreatable fibrotic
disease of unknown origin. We investigated the contribution of the B-cell activating factor …

Interleukin 26 (IL-26) is the most recently identified member of the IL-20 cytokine subfamily,
and is a novel mediator of inflammation overexpressed in activated or transformed T cells …

Objective Although Tc17 lymphocytes are enriched in the central nervous system (CNS) of
multiple sclerosis (MS) subjects and of experimental autoimmune encephalomyelitis (EAE) …

Chronic graft-versus-host disease (cGvHD) remains a major complication of allogeneic stem
cell transplantation requiring novel therapies. CD146 and CCR5 are expressed by activated …