Passive, active and endogenous organ-targeted lipid and polymer nanoparticles for delivery of genetic drugs

SA Dilliard, DJ Siegwart - Nature Reviews Materials, 2023 - nature.com
Genetic drugs based on nucleic acid biomolecules are a rapidly emerging class of
medicines that directly reprogramme the central dogma of biology to prevent and treat …

Nanotechnology: A revolution in modern industry

S Malik, K Muhammad, Y Waheed - Molecules, 2023 - mdpi.com
Nanotechnology, contrary to its name, has massively revolutionized industries around the
world. This paper predominantly deals with data regarding the applications of …

Targeting drugs to tumours using cell membrane-coated nanoparticles

RH Fang, W Gao, L Zhang - Nature Reviews Clinical Oncology, 2023 - nature.com
Traditional cancer therapeutics, such as chemotherapies, are often limited by their non-
specific nature, causing harm to non-malignant tissues. Over the past several decades …

The blood–brain barrier: structure, regulation, and drug delivery

D Wu, Q Chen, X Chen, F Han, Z Chen… - Signal Transduction and …, 2023 - nature.com
Blood–brain barrier (BBB) is a natural protective membrane that prevents central nervous
system (CNS) from toxins and pathogens in blood. However, the presence of BBB …

Cancer nanomedicine

SN Bhatia, X Chen, MA Dobrovolskaia… - Nature Reviews …, 2022 - nature.com
The field of cancer nanomedicine seeks to overcome the inherent shortcomings of
conventional cancer diagnostics and therapies. Yet despite the surge of interest in and …

Engineering mesoporous silica nanoparticles for drug delivery: where are we after two decades?

M Vallet-Regí, F Schüth, D Lozano, M Colilla… - Chemical Society …, 2022 - pubs.rsc.org
The present review details a chronological description of the events that took place during
the development of mesoporous materials, their different synthetic routes and their use as …

Smart nanoparticles for cancer therapy

L Sun, H Liu, Y Ye, Y Lei, R Islam, S Tan… - Signal transduction and …, 2023 - nature.com
Smart nanoparticles, which can respond to biological cues or be guided by them, are
emerging as a promising drug delivery platform for precise cancer treatment. The field of …

Molecular probes, chemosensors, and nanosensors for optical detection of biorelevant molecules and ions in aqueous media and biofluids

J Krämer, R Kang, LM Grimm, L De Cola… - Chemical …, 2022 - ACS Publications
Synthetic molecular probes, chemosensors, and nanosensors used in combination with
innovative assay protocols hold great potential for the development of robust, low-cost, and …

Lipid nanoparticles─ from liposomes to mRNA vaccine delivery, a landscape of research diversity and advancement

R Tenchov, R Bird, AE Curtze, Q Zhou - ACS nano, 2021 - ACS Publications
Lipid nanoparticles (LNPs) have emerged across the pharmaceutical industry as promising
vehicles to deliver a variety of therapeutics. Currently in the spotlight as vital components of …

The evolution of commercial drug delivery technologies

AM Vargason, AC Anselmo, S Mitragotri - Nature biomedical …, 2021 - nature.com
Drug delivery technologies have enabled the development of many pharmaceutical
products that improve patient health by enhancing the delivery of a therapeutic to its target …