Epigenetic dysfunction has been widely implicated in several diseases especially cancers
thus highlights the therapeutic potential for chemical interventions in this field. With rapid …

Peptides have gained increased interest as therapeutics during recent years. More than 60
peptide drugs have reached the market for the benefit of patients and several hundreds of …

Parkinson's disease (PD) is the second most common neurodegenerative disorder caused
due to loss of dopaminergic neurons in substantia nigra pars compacta, which occurs the …

This chapter outlines state-of-the art computational chemistry techniques that can be used to
develop mechanistic descriptors for predictive models. For the reader to gain appreciation …

Through experimental information available from antioxidant assays of seventeen
anthocyanins, and six common anthocyanidins, quantitative structure–activity relationships …

The quantitative structural property relationship (QSPR) models of the logβ 11 stability
constants of M: L complexes of the structurally diverse thiosemicarbazones and several …

A novel model is presented for reliable estimation of the stability constants of the
thiosemicarbazone ligands with different types of toxic heavy metal ions (log β 11) in an …

Many biochemical reactions are based on redox reactions. Therefore, the redox potential of
a chemical compound may be related to its therapeutic or physiological effects. The study of …

Chagas and leishmaniasis are two neglected diseases considered as public health
problems worldwide, for which there is no effective, low-cost, and low-toxicity treatment for …

This study authenticated fish feed sources and determined lard adulteration using dataset
pre-processing, principal component analysis (PCA), discriminant analysis (DA) and partial …