Resistance that stacks up: engineering rust and mildew disease control in the cereal crops wheat and barley
PM Dracatos, J Lu, J Sánchez‐Martín… - Plant biotechnology …, 2023 - Wiley Online Library
Staying ahead of the arms race against rust and mildew diseases in cereal crops is essential
to maintain and preserve food security. The methodological challenges associated with …
to maintain and preserve food security. The methodological challenges associated with …
[HTML][HTML] Seeing is believing: Exploiting advances in structural biology to understand and engineer plant immunity
MA Outram, M Figueroa, J Sperschneider… - Current Opinion in Plant …, 2022 - Elsevier
Filamentous plant pathogens cause disease in numerous economically important crops.
These pathogens secrete virulence proteins, termed effectors, that modulate host cellular …
These pathogens secrete virulence proteins, termed effectors, that modulate host cellular …
[HTML][HTML] A wheat resistosome defines common principles of immune receptor channels
A Förderer, E Li, AW Lawson, Y Deng, Y Sun… - Nature, 2022 - nature.com
Plant intracellular nucleotide-binding leucine-rich repeat receptors (NLRs) detect pathogen
effectors to trigger immune responses. Indirect recognition of a pathogen effector by the …
effectors to trigger immune responses. Indirect recognition of a pathogen effector by the …
[HTML][HTML] Prediction of effector protein structures from fungal phytopathogens enables evolutionary analyses
K Seong, KV Krasileva - Nature Microbiology, 2023 - nature.com
Elucidating the similarity and diversity of pathogen effectors is critical to understand their
evolution across fungal phytopathogens. However, rapid divergence that diminishes …
evolution across fungal phytopathogens. However, rapid divergence that diminishes …
Altering specificity and autoactivity of plant immune receptors Sr33 and Sr50 via a rational engineering approach
Many resistance genes deployed against pathogens in crops are intracellular nucleotide-
binding (NB) leucine-rich repeat (LRR) receptors (NLRs). The ability to rationally engineer …
binding (NB) leucine-rich repeat (LRR) receptors (NLRs). The ability to rationally engineer …
Structural polymorphisms within a common powdery mildew effector scaffold as a driver of coevolution with cereal immune receptors
Y Cao, F Kümmel, E Logemann… - Proceedings of the …, 2023 - National Acad Sciences
In plants, host–pathogen coevolution often manifests in reciprocal, adaptive genetic
changes through variations in host nucleotide-binding leucine-rich repeat immune receptors …
changes through variations in host nucleotide-binding leucine-rich repeat immune receptors …
[HTML][HTML] Pathways to engineering plant intracellular NLR immune receptors
R Zdrzałek, C Stone, JC De la Concepcion… - Current Opinion in Plant …, 2023 - Elsevier
Factors including climate change and increased global exchange are set to escalate the
prevalence of plant diseases, posing an unprecedented threat to global food security and …
prevalence of plant diseases, posing an unprecedented threat to global food security and …
Direct recognition of pathogen effectors by plant NLR immune receptors and downstream signalling
Plants deploy extracellular and intracellular immune receptors to sense and restrict
pathogen attacks. Rapidly evolving pathogen effectors play crucial roles in suppressing …
pathogen attacks. Rapidly evolving pathogen effectors play crucial roles in suppressing …
[HTML][HTML] Barley MLA3 recognizes the host-specificity effector Pwl2 from Magnaporthe oryzae
HJ Brabham, D Gómez De La Cruz, V Were… - The Plant …, 2024 - academic.oup.com
Plant nucleotide-binding leucine-rich repeat (NLRs) immune receptors directly or indirectly
recognize pathogen-secreted effector molecules to initiate plant defense. Recognition of …
recognize pathogen-secreted effector molecules to initiate plant defense. Recognition of …
[HTML][HTML] The structural repertoire of Fusarium oxysporum f. sp. lycopersici effectors revealed by experimental and computational studies
Plant pathogens secrete proteins, known as effectors, that function in the apoplast or inside
plant cells to promote virulence. Effector recognition by cell-surface or cytosolic receptors …
plant cells to promote virulence. Effector recognition by cell-surface or cytosolic receptors …