Activated ester containing polymers: opportunities and challenges for the design of functional macromolecules

A Das, P Theato - Chemical reviews, 2016 - ACS Publications
Rapidly growing demand of functional polymers in various interdisciplinary areas of
research has accentuated the need for modern synthetic tools to develop advanced …

Update and challenges in organo-mediated polymerization reactions

WN Ottou, H Sardon, D Mecerreyes, J Vignolle… - Progress in Polymer …, 2016 - Elsevier
Organocatalysis has become a very powerful tool for precision macromolecular chemistry,
as judged by the number of articles published in this field in the past decade. A variety of …

Poly (trimethylene carbonate)-based polymers engineered for biodegradable functional biomaterials

K Fukushima - Biomaterials science, 2016 - pubs.rsc.org
Aliphatic polycarbonates have drawn attention as biodegradable polymers that can be
applied to a broad range of resorbable medical devices. In particular, poly (trimethylene …

Synthesis of polyurethanes using organocatalysis: A perspective

H Sardon, A Pascual, D Mecerreyes, D Taton… - …, 2015 - ACS Publications
Organocatalysis has become an invaluable tool for polymer synthesis, and its utility has
been demonstrated in ring-opening, anionic, zwitterionic, and group-transfer …

Functional biodegradable polymers via ring-opening polymerization of monomers without protective groups

G Becker, FR Wurm - Chemical society reviews, 2018 - pubs.rsc.org
Biodegradable polymers are of current interest and chemical functionality in such materials
is often demanded in advanced biomedical applications. Functional groups often are not …

Protein–polymer conjugation—moving beyond PEGylation

Y Qi, A Chilkoti - Current opinion in chemical biology, 2015 - Elsevier
Highlights•Limitations of conjugating poly (ethylene glycol) to proteins and peptides have
become increasingly apparent.•Various polymers have shown promise as PEG …

Macromolecular architectures through organocatalysis

S Hu, J Zhao, G Zhang, H Schlaad - Progress in Polymer Science, 2017 - Elsevier
In virtue of the rising demand for metal-free polymeric materials, organocatalytic
polymerization has emerged and blossomed unprecedentedly in the past 15 years into an …

Renaissance of aliphatic polycarbonates: New techniques and biomedical applications

J Xu, E Feng, J Song - Journal of Applied Polymer Science, 2014 - Wiley Online Library
Aliphatic polycarbonates (APCs) were discovered a long time ago, with their conventional
applications mostly limited to low‐molecular‐weight oligomeric intermediates for …

Ring‐opening polymerization of prodrugs: a versatile approach to prepare well‐defined drug‐loaded nanoparticles

J Liu, W Liu, I Weitzhandler… - Angewandte Chemie …, 2015 - Wiley Online Library
The synthesis of polymer–drug conjugates from prodrug monomers consisting of a cyclic
polymerizable group that is appended to a drug through a cleavable linker is achieved by …

pH-sensitive nanodrug carriers for codelivery of ERK inhibitor and gemcitabine enhance the inhibition of tumor growth in pancreatic cancer

P Ray, D Dutta, I Haque, G Nair… - Molecular …, 2020 - ACS Publications
Pancreatic ductal adenocarcinoma (PDAC), a metabolic disorder, remains one of the
leading cancer mortality sources worldwide. An initial response to treatments, such as …