Supercritical carbon dioxide extraction of plant phytochemicals for biological and environmental applications–A review

T Arumugham, K Rambabu, SW Hasan, PL Show… - Chemosphere, 2021 - Elsevier
Recently, supercritical fluid CO 2 extraction (SFE) has emerged as a promising and
pervasive technology over conventional extraction techniques for various applications …

[HTML][HTML] Therapeutic role of alkaloids and alkaloid derivatives in cancer management

K Olofinsan, H Abrahamse, BP George - Molecules, 2023 - mdpi.com
Cancer is a neoplastic disease that remains a global challenge with a reported prevalence
that is increasing annually. Though existing drugs can be applied as single or combined …

Coumarin derivatives with anticancer activities: An update

XF Song, J Fan, L Liu, XF Liu, F Gao - Archiv der Pharmazie, 2020 - Wiley Online Library
Cancer can invade or spread to almost all parts of the body. The increasing morbidity and
high mortality of cancer create a great demand for the development of novel anticancer …

[HTML][HTML] Coumarins as fungal metabolites with potential medicinal properties

OM Tsivileva, OV Koftin, NV Evseeva - Antibiotics, 2022 - mdpi.com
Coumarins are a structurally varied set of 2 H-chromen-2-one compounds categorized also
as members of the benzopyrone group of secondary metabolites. Coumarin derivatives …

Current status of carbazole hybrids as anticancer agents

G Wang, S Sun, H Guo - European Journal of Medicinal Chemistry, 2022 - Elsevier
The drug resistance and low specificity of current available chemotherapeutics to cancer
cells are the main reasons responsible for the failure of cancer chemotherapy and remain …

[HTML][HTML] Latest developments in coumarin-based anticancer agents: mechanism of action and structure–activity relationship studies

M Koley, J Han, VA Soloshonok… - RSC Medicinal …, 2024 - ncbi.nlm.nih.gov
Many researchers around the world are working on the development of novel anticancer
drugs with different mechanisms of action. In this case, coumarin is a highly promising …

[HTML][HTML] Phyto-carbazole alkaloids from the rutaceae family as potential protective agents against neurodegenerative diseases

MA Tan, N Sharma, SSA An - Antioxidants, 2022 - mdpi.com
Plant-derived (phyto) carbazole alkaloids are an important class of compounds, presented in
the family of Rutaceae (Genera Murraya, Clausena, Glycosmis, Micromelum and …

[HTML][HTML] Design, synthesis, molecular docking and biological evaluation of new carbazole derivatives as anticancer, and antioxidant agents

İ Çapan, M Hawash, N Jaradat, Y Sert, R Servi, İ Koca - BMC chemistry, 2023 - Springer
Background The carbazole skeleton is an important structural motif occurring naturally or
synthesized chemically and has antihistaminic, antioxidant, antitumor, antimicrobial, and anti …

[HTML][HTML] In silico analysis and identification of antiviral coumarin derivatives against 3-chymotrypsin-like main protease of the novel coronavirus SARS-CoV-2

R Abdizadeh, F Hadizadeh, T Abdizadeh - Molecular Diversity, 2022 - Springer
Abstract Coronavirus disease 2019 (COVID-19) is a pandemic viral disease caused by
SARS-CoV-2 that generated serious damages for both the human population and the global …

Comprehensive Review of Phytochemical Profiles and Health-Promoting Effects of Different Portions of Wampee (Clausena lansium)

X Huang, M Wang, S Zhong, B Xu - ACS omega, 2023 - ACS Publications
Clausena lansium, commonly known as wampee, is a subtropical fruit from the Rutaceae
family characterized by its high nutrient content and numerous bioactive substances. This …