Voltage gated sodium channel inhibitors as anticonvulsant drugs: A systematic review on recent developments and structure activity relationship studies

R Pal, B Kumar, MJ Akhtar, PA Chawla - Bioorganic Chemistry, 2021 - Elsevier
Voltage-gated sodium channel blockers are one of the vital targets for the management of
several central nervous system diseases, including epilepsy, chronic pain, psychiatric …

An overview on the recent developments of 1, 2, 4-triazine derivatives as anticancer compounds

S Cascioferro, B Parrino, V Spano, A Carbone… - European Journal of …, 2017 - Elsevier
The synthesis, the antitumor activity, the SAR and, whenever described, the possible mode
of action of 1, 2, 4-triazine derivatives, their N-oxides, N, N′-dioxides as well as the benzo …

Investigation on corrosion inhibition and adsorption mechanism of triazine-thiourea derivatives at mild steel/HCl solution interface: Electrochemical, XPS, DFT and …

PK Paul, M Yadav - Journal of Electroanalytical Chemistry, 2020 - Elsevier
The corrosion inhibition behavior of synthesized triazine-thiourea compounds, namely, 1, 3-
bis (5, 6-diphenyl-1, 2, 4-triazin-3-yl) thiourea (BTT) and 1, 3-bis (5H-[1, 2, 4] triazino [5, 6-b] …

Triazines as a potential class of corrosion inhibitors: Present scenario, challenges and future perspectives

DS Chauhan, MA Quraishi, WBW Nik… - Journal of Molecular …, 2021 - Elsevier
The triazine molecule is a major member of the family of the heterocyclic compounds, which
occurs in a wide range of pharmaceutical ingredients and natural products. A number of …

Treatment of toxoplasmosis and neosporosis in farm ruminants: state of knowledge and future trends

R Sánchez-Sánchez, P Vázquez, I Ferre… - Current topics in …, 2018 - ingentaconnect.com
Toxoplasmosis and neosporosis are closely related protozoan diseases that lead to
important economic impacts in farm ruminants. Toxoplasma gondii infection mainly causes …

Synthesis, biological activity and molecular modeling study of novel 1,2,4-triazolo[4,3-b][1,2,4,5]tetrazines and 1,2,4-triazolo[4,3-b][1,2,4]triazines

AAM El-Reedy, NK Soliman - Scientific reports, 2020 - nature.com
Abstract Different novel 1, 2, 4-triazolo [4, 3-b][1, 2, 4, 5] tetrazines and 1, 2, 4-triazolo [4, 3-
b][1, 2, 4] triazines have been obtained from heterocyclization of 3-substituted-4-amino-5 …

Synthesis, biological evaluation, and docking studies of novel 5, 6-diaryl-1, 2, 4-triazine thiazole derivatives as a new class of α-glucosidase inhibitors

G Wang, Z Peng, Z Gong, Y Li - Bioorganic Chemistry, 2018 - Elsevier
Abstract A novel 5, 6-diaryl-1, 2, 4-triazine thiazole derivatives (7a-7q) were synthesized and
characterized by 1 H NMR and 13 C NMR and evaluated for their α-glucosidase inhibitory …

Synthesis of new pyrazoles, oxadiazoles, triazoles, pyrrolotriazines, and pyrrolotriazepines as potential cytotoxic agents

AA Abu‐Hashem - Journal of Heterocyclic Chemistry, 2021 - Wiley Online Library
Oxo‐4‐phenylbutanehydrazide (1) reacted with many active methylene reagents such as
acetylacetone, diethylmalonate, ethylacetoacetate, ethylcyanoacetate, benzoyl‐acetonitrile …

Quinazolinone-based hybrids with diverse biological activities: A mini-review

R Rezaeinasab, E Jafari… - Journal of Research in …, 2022 - journals.lww.com
Quinazolinone and quinazoline have been shown different pharmacological activities,
namely anticancer, anti-inflammatory, anti-hyperlipidemia, analgesic, antihypertensive, and …

Design, synthesis of 1, 2, 4-triazine derivatives as antidepressant and antioxidant agents: In vitro, in vivo and in silico studies

R Pal, B Kumar, GS PM, PA Chawla - Bioorganic Chemistry, 2023 - Elsevier
The novel series of substituted-N-(5, 6-diphenyl-1, 2, 4-triazin-3-yl) benzamides (R: 1–12)
were designed, synthesized and evaluated for in-vitro and in-vivo antidepressant-like …