Alzheimer's disease as type 3 diabetes: common pathophysiological mechanisms between Alzheimer's disease and type 2 diabetes

M Michailidis, D Moraitou, DA Tata, K Kalinderi… - International journal of …, 2022 - mdpi.com
Globally, the incidence of type 2 diabetes mellitus (T2DM) and Alzheimer's disease (AD)
epidemics is increasing rapidly and has huge financial and emotional costs. The purpose of …

Association of sleep-disordered breathing with cognitive function and risk of cognitive impairment: a systematic review and meta-analysis

Y Leng, CT McEvoy, IE Allen, K Yaffe - JAMA neurology, 2017 - jamanetwork.com
Importance Growing evidence suggests an association between sleep-disordered breathing
(SDB) and cognitive decline in elderly persons. However, results from population-based …

Antioxidants in Alzheimer's disease: Current therapeutic significance and future prospects

P Pritam, R Deka, A Bhardwaj, R Srivastava, D Kumar… - Biology, 2022 - mdpi.com
Simple Summary Alzheimer's disease (AD) is the most common neurodegenerative disease,
intensifying impairments in cognition, behavior, and memory. Histopathological AD …

Oxidative stress in Alzheimer's disease

Z Chen, C Zhong - Neuroscience bulletin, 2014 - Springer
Oxidative stress plays a significant role in the pathogenesis of Alzheimer's disease (AD), a
devastating disease of the elderly. The brain is more vulnerable than other organs to …

Correlation of Alzheimer disease neuropathologic changes with cognitive status: a review of the literature

PT Nelson, I Alafuzoff, EH Bigio… - … of Neuropathology & …, 2012 - academic.oup.com
Clinicopathologic correlation studies are critically important for the field of Alzheimer disease
(AD) research. Studies on human subjects with autopsy confirmation entail numerous …

Oxidative stress and the pathogenesis of Alzheimer′ s disease

Y Zhao, B Zhao - Oxidative medicine and cellular longevity, 2013 - Wiley Online Library
Alzheimer′ s disease (AD) is the most common neurodegenerative disease that causes
dementia in the elderly. Patients with AD suffer a gradual deterioration of memory and other …

Linking oxidative stress and proteinopathy in Alzheimer's disease

C Sharma, SR Kim - Antioxidants, 2021 - mdpi.com
Proteinopathy and excessive production of reactive oxygen species (ROS), which are the
principal features observed in the Alzheimer's disease (AD) brain, contribute to neuronal …

[HTML][HTML] Alzheimer disease

RJ Castellani, RK Rolston, MA Smith - Disease-a-month: DM, 2010 - ncbi.nlm.nih.gov
In 1907, Alois Alzheimer described the case of a 51 year old woman who presented with a
relatively rapidly deteriorating memory along with psychiatric disturbances. She died four …

Impaired balance of mitochondrial fission and fusion in Alzheimer's disease

X Wang, BO Su, H Lee, X Li, G Perry… - Journal of …, 2009 - Soc Neuroscience
Mitochondrial dysfunction is a prominent feature of Alzheimer's disease (AD) neurons. In this
study, we explored the involvement of an abnormal mitochondrial dynamics by investigating …

Long-term air pollution exposure is associated with neuroinflammation, an altered innate immune response, disruption of the blood-brain barrier, ultrafine particulate …

L Calderón-Garcidueñas, AC Solt… - Toxicologic …, 2008 - journals.sagepub.com
Air pollution is a serious environmental problem. We investigated whether residency in cities
with high air pollution is associated with neuroinflammation/neurodegeneration in healthy …