The blood–brain barrier (BBB) is a dynamic interface responsible for maintaining the central
nervous system homeostasis. Its unique characteristics allow protecting the brain from …

Of the neurogenic zones in the adult brain, adult hippocampal neurogenesis attracts the
most attention, because it is involved in higher cognitive function, most notably memory …

Human pluripotent stem cells have emerged as a promising in vitro model system for
studying the brain. Two-dimensional and three-dimensional cell culture paradigms have …

Adult neurogenesis in the hippocampus is a notable process due not only to its uniqueness
and potential impact on cognition but also to its localized vertical integration of different …

There is a growing body of evidence demonstrating that stress decreases the expression of
brain-derived neurotrophic factor (BDNF) in limbic structures that control mood and that …

Previously undescribed prognostic subclasses of high-grade astrocytoma are identified and
discovered to resemble stages in neurogenesis. One tumor class displaying neuronal …

The family of vascular endothelial growth factors (VEGFs) are known for their regulation of
vascularization. In the brain, VEGFs are important regulators of angiogenesis …

Astrocyte-like cells, which act as stem cells in the adult brain, reside in a few restricted stem
cell niches. However, following brain injury, glia outside these niches acquire or reactivate …

Background Vascular endothelial growth factor (VEGF) is well known for its role in normal
and pathologic neovascularization. However, a growing body of evidence indicates that …

Coping with stress is fundamental for mental health, but understanding of the molecular
neurobiology of stress is still in its infancy. Adult neurogenesis is well known to be regulated …