In the last few years, the pyridazine derivatives have been found to exhibit a wide range of
pharmacological activities. A large number of research articles and patents described them …

In this study new 6-substituted-3 (2H)-pyridazinone-2-acetyl-2-(p-substituted benzal)
hydrazone V derivatives were synthesized as analgesic and anti-inflammatory agents. The …

In this study, two series of 35 new chalcone derivatives containing aryl-piperazine or aryl-
sulfonyl-piperazine fragment were synthesized and their structures were characterized by 1 …

Numerous studies have confirmed the coexistence of oxidative stress and inflammatory
processes. Long-term inflammation and oxidative stress may significantly affect the initiation …

Arylpiperazine‐based dopaminergic/serotonergic ligands exert neuroprotective activity. We
examined the effect of arylpiperazine D2/5‐HT 1A ligands, N‐{4‐[2‐(4‐phenyl‐piperazin‐1 …

In this study thirteen 6-substituted-3 (2H)-pyridazinone-2-acetyl-2-(substituted/-
nonsubstituted benzal) hydrazone V derivatives were synthesized as acetylcholinesterase …

The difficulty in managing tuberculosis includes the prolonged duration of the treatment, the
emergence of drug resistance, and coinfection with HIV/AIDS. Tuberculosis control requires …

Eleven antipyrine/pyridazinone hybrids were synthesized and evaluated for their in vivo
analgesic and anti-inflammatory activities by p-benzoquinone-induced writhing test and …

In the current study, some novel ethyl 6-[(substituted-phenylpiperazine]-3 (2H)-pyridazinone-
2-yl propionate III and 6-[(substituted-phenylpiperazine]-3 (2H)-pyridazinone-2-yl …

For reducing gastrointestinal toxicity associated with non-steroidal anti-inflammatory drugs
(NSAIDs) a variety of 6-phenyl/(4-methylphenyl)-3 (2H)-pyridazi-non-2-propionamide were …