The impact of proteins and peptides on the treatment of various conditions including ocular
diseases over the past few decades has been advanced by substantial breakthroughs in …

Introduction: Proteins are effective biotherapeutics with applications in diverse ailments.
Despite being specific and potent, their full clinical potential has not yet been realized. This …

Polymeric materials obtained from petroleum resources are nonbiodegradable. Defying
degradation, they damage the environment as a result of their ending up in the landfills …

Therapeutic proteins, including monoclonal antibodies, single chain variable fragment
(ScFv), crystallizable fragment (Fc), and fragment antigen binding (Fab), have accounted for …

Age-related ocular diseases, such as age-related macular degeneration (AMD), diabetic
retinopathy, and glaucoma, result in life-long functional deficits and enormous global health …

Highlights•Hydrogels provide a flexible platform for design of ocular delivery
systems.•Intraocular injection of hydrogels can be accomplished via several …

Introduction: Biologics are generally macromolecules, large in size with poor stability in
biological environments. Delivery of biologics to tissues at the back of the eye remains a …

Age-related macular degeneration (AMD) is one of the leading causes of blindness in the
US affecting millions yearly. It is characterized by intraocular neovascularization …

The purpose of this investigation is to design and synthesize novel pentablock (PB)
copolymer (PB-1: PCL–PLA–PEG–PLA–PCL) based nanoformulations suspended in a …

In this review, we present current state-of-the-art developments and challenges in the areas
of thermal therapy, ultrasound tomography, image-guided therapies, ocular drug delivery …