Immunocompetent mouse models in the search for effective immunotherapy in glioblastoma
R Wouters, S Bevers, M Riva, F De Smet… - Cancers, 2020 - mdpi.com
Simple Summary Glioblastoma (GBM) remains the most aggressive brain tumor. Treatment
typically includes surgery and radio/chemotherapy, but in spite of intensive treatment …
typically includes surgery and radio/chemotherapy, but in spite of intensive treatment …
Anti-PD-1 checkpoint blockade monotherapy in the orthotopic GL261 glioma model: The devil is in the detail
ZP Tritz, K Ayasoufi, AJ Johnson - Neuro-oncology advances, 2021 - academic.oup.com
The GL261 cell line, syngeneic on the C57BL/6 background, has, since its establishment
half a century ago in 1970, become the most commonly used immunocompetent murine …
half a century ago in 1970, become the most commonly used immunocompetent murine …
Flagellin synergistically enhances anti-tumor effect of EGFRvIII peptide in a glioblastoma-bearing mouse brain tumor model
JM Choi, SH Lim, ZP Liu, TK Lee, JH Rhee, MS Yoon… - BMC cancer, 2022 - Springer
Background Glioblastoma (GBM) is the most aggressive type of brain tumor with
heterogeneity and strong invasive ability. Treatment of GBM has not improved significantly …
heterogeneity and strong invasive ability. Treatment of GBM has not improved significantly …
Incorporation of a TGF-β2-inhibiting oligodeoxynucleotide molecular adjuvant into a tumor cell lysate vaccine to enhance antiglioma immunity in mice
L Tu, Z Wang, L Yang, X Sun, Y Yao, P Zhang… - Frontiers in …, 2023 - frontiersin.org
Introduction Transforming growth factor β2 (TGF-β2), also known as glioma-derived T-cell
suppressor factor, is associated with the impairment of tumor immune surveillance …
suppressor factor, is associated with the impairment of tumor immune surveillance …
A hybrid glioma tumor cell lysate immunotherapy vaccine demonstrates good clinical efficacy in the rat model
XL Li, S Zeng, HP He, X Zeng, LL Peng… - OncoTargets and …, 2020 - Taylor & Francis
Background Conventional immunotherapy for glioma is not only expensive but also
demonstrates less-than-desired clinical efficacy. In this study, we evaluated the …
demonstrates less-than-desired clinical efficacy. In this study, we evaluated the …
Recombinant Domain of Flagellin Promotes In Vitro a Chemotactic Inflammatory Profile in Human Immune Cells Independently of a Dendritic Cell Phenotype
R González-Stegmaier, A Aguirre, C Cárcamo… - Molecules, 2023 - mdpi.com
Flagellin is the major component of the flagellum in gram-positive and-negative bacteria and
is also the ligand for the Toll-like receptor 5 (TLR5). The activation of TLR5 promotes the …
is also the ligand for the Toll-like receptor 5 (TLR5). The activation of TLR5 promotes the …
[PDF][PDF] Im-munocompetent Mouse Models in the Search for Effective Immunotherapy in Glioblastoma. Cancers 2021, 13, 19
R Wouters, S Bevers, M Riva, F De Smet… - 2020 - academia.edu
Glioblastoma (GBM) is the most aggressive intrinsic brain tumor in adults. Despite maximal
therapy consisting of surgery and radio/chemotherapy, GBM remains largely incurable with …
therapy consisting of surgery and radio/chemotherapy, GBM remains largely incurable with …