Lupus nephritis

HJ Anders, R Saxena, M Zhao, I Parodis… - Nature reviews Disease …, 2020 - nature.com
Lupus nephritis (LN) is a form of glomerulonephritis that constitutes one of the most severe
organ manifestations of the autoimmune disease systemic lupus erythematosus (SLE). Most …

[HTML][HTML] A review of complement activation in SLE

A Weinstein, RV Alexander, DJ Zack - Current rheumatology reports, 2021 - Springer
Abstract Purpose of Review Complement activation is a key event in the pathogenesis of
tissue inflammation and injury in systemic lupus erythematosus (SLE). This review is aimed …

The British Society for Rheumatology guideline for the management of systemic lupus erythematosus in adults

C Gordon, MB Amissah-Arthur, M Gayed… - …, 2018 - academic.oup.com
Caroline Gordon1, 2, 3, Maame-Boatemaa Amissah-Arthur1, Mary Gayed1, 3, Sue Brown4,
Ian N. Bruce5, 6, David D'Cruz7, Benjamin Empson8, Bridget Griffiths9, David Jayne10, 11 …

[HTML][HTML] Joint European League Against Rheumatism and European Renal Association–European Dialysis and Transplant Association (EULAR/ERA-EDTA) …

GK Bertsias, M Tektonidou, Z Amoura… - Annals of the …, 2012 - ard.bmj.com
Objectives To develop recommendations for the management of adult and paediatric lupus
nephritis (LN). Methods The available evidence was systematically reviewed using the …

[HTML][HTML] Clinical and immunological biomarkers for systemic lupus erythematosus

H Yu, Y Nagafuchi, K Fujio - Biomolecules, 2021 - mdpi.com
Systemic lupus erythematosus (SLE) is characterized by immune system dysfunction and is
clinically heterogeneous, exhibiting renal, dermatological, neuropsychiatric, and …

Update on lupus nephritis: looking for a new vision

E Morales, M Galindo, H Trujillo, M Praga - Nephron, 2021 - karger.com
Lupus nephritis (LN) is one of the most common manifestations of systemic lupus
erythematosus (SLE), affecting approximately 40% of patients with lupus. It represents a …

[HTML][HTML] B cell abnormalities in systemic lupus erythematosus and lupus nephritis—role in pathogenesis and effect of immunosuppressive treatments

DYH Yap, TM Chan - International journal of molecular sciences, 2019 - mdpi.com
Abnormalities in B cells play pivotal roles in the pathogenesis of systemic lupus
erythematosus (SLE) and lupus nephritis (LN). Breach in central and peripheral tolerance …

Lupus nephritis: a critical review

AT Borchers, N Leibushor, SM Naguwa… - Autoimmunity …, 2012 - Elsevier
Lupus nephritis remains one of the most severe manifestations of systemic lupus
erythematosus associated with considerable morbidity and mortality. A better understanding …

The lupus nephritis management renaissance

JM Mejia-Vilet, A Malvar, A Arazi, BH Rovin - Kidney International, 2022 - Elsevier
Over the past year, and for the first time ever, the US Food and Drug Administration
approved 2 drugs specifically for the treatment of lupus nephritis (LN). As the lupus …

Lupus nephritis biomarkers

S Soliman, C Mohan - Clinical immunology, 2017 - Elsevier
Lupus nephritis (LN), a potentially destructive outcome of SLE, is a real challenge in the
management of SLE because of the difficulty in diagnosing its subclinical onset and …