Nesfatin-1 was discovered in 2006 and implicated in the regulation of food intake.
Subsequently, its widespread central and peripheral distribution gave rise to additional …

Background Nesfatin-1 is an 82-amino acid polypeptide, cleaved from the 396-amino acid
precursor protein nucleobindin-2 (NUCB2) and discovered in 2006 in the rat hypothalamus …

Since its discovery in 2006 by Oh-I and colleagues, NUCB2/nesfatin-1 encoded by
nucleobindin-2 (NUCB2) has drawn sustained attention as reflected in over 500 …

Appetite is controlled by a complex system of central and peripheral signals interacting to
modulate the ingestion response. Several brain mediators with complex networks adjust …

Abstract Background & Aim Adiponectin is a member of the adipokine family and contributes
to regulating energy homeostasis, reproduction, and various biological functions, such as …

Previous studies have shown the role of apelin and its receptors in the regulation of food
intake. In the present study, we investigate the mediating role of melanocortin, corticotropin …

Animal research indicates the neuropeptide Y (NPY), corticotrophin and melanocortin
systems have a mediatory role in reward, however, how these substances interact with …

Evidence from animal studies suggests that the opioidergic system and ghrelin have a
regulatory role in food intake, but their interaction (s) have not been studied in laying …

Ghrelin was first identified as an endogenous ligand of the growth hormone secretagogue
receptor (GHSR) in 1999, with the function of stimulating the release of growth hormone …

Abstract Nucleobindin-derived peptides, nesfatin-1 [NESF-1] and nesfatin-1-like-peptide
[NLP] have diverse roles in endocrine and metabolic regulation. While both peptides …