Colorectal cancer is one of the most prevalent cancers with high mortality in the world.
MicroRNAs are a class of small non-coding RNAs that regulate gene expression through …

The mesodiencephalic dopaminergic (mdDA) group of neurons comprises molecularly
distinct subgroups, of which the substantia nigra (SN) and ventral tegmental area (VTA) are …

The establishment of the anteroposterior (AP) axis is a crucial step during animal embryo
development. In mammals, genetic studies have shown that this process relies on signals …

In severe early-onset epilepsy, precise clinical and molecular genetic diagnosis is complex,
as many metabolic and electro-physiological processes have been implicated in disease …

Gene regulatory networks controlling functional activities of spatially and temporally distinct
endodermal cell populations in the early mouse embryo remain ill defined. The T-box …

p53 is a bona fide tumor suppressor gene whose loss of function marks the most common
genetic alteration in human malignancy. Although the causal link between loss of p53 …

This paper aims to explore a potential connection between two hypotheses recently put
forward in the context of language evolution. One hypothesis argues that some human …

Research from the last 15 years has provided a working model for how the anterior forebrain
is induced and specified during the early stages of embryogenesis. This model relies on …

Embryonic development and adult homeostasis are dependent upon the coordinated action
of signal transduction pathways such as the Wnt signalling pathway which is used iteratively …

Primary cilia are organelles extended from virtually all cells and are required for the proper
regulation of a number of canonical developmental pathways. The role in cortical …