Over the past two decades, bioorthogonal chemistry has undergone a remarkable
development, challenging traditional assumptions in biology and medicine. Recent …

The assembly of metal–organic cages is governed by metal ion coordination preferences
and the geometries of the typically rigid and planar precursor ligands. Pd n L2 n cages are …

Various fluorogenic probes utilizing tetrazine (Tz) as a fluorescence quencher and
bioorthogonal reaction partner have been extensively studied over the past few decades …

An orange‐and a red‐emitting tetrazine‐modified cyanine‐styryl dyes were synthesized for
bioorthogonal labelling of DNA by means of the Diels‐Alder reaction with inverse electron …

Fluorogenic bioorthogonal reactions are promising tools for tracking small molecules or
biomolecules in living organisms. Two-photon excitation, by shifting absorption towards the …

Fluorescence imaging, a key technique in biological research, frequently utilizes fluorogenic
probes for precise imaging in living systems. Tetrazine is an effective emission quencher in …

Hepatocellular carcinoma (HCC) is a top contributor to cancer-related deaths making early
diagnosis crucial. However, current surveillance techniques are inadequate in early stages …