The intrinsic electrical properties and the synaptic input-output relationships of neurons are
governed by the action of voltage-dependent ion channels. The localization of specific …

Potassium channels play important roles in vital cellular signaling processes in both
excitable and nonexcitable cells. Over 50 human genes encoding various K+ channels have …

Potassium channels share a highly conserved stretch of eight amino acids, a K+ channel
signature sequence. The conserved sequence falls within the previously defined P-region of …

A complementary DNA encoding an inward rectifier K+ channel (IRK1) was isolated from a
mouse macrophage cell line by expression cloning. This channel conducts inward K+ …

A complementary DNA encoding an ATP-regulated potassium channel has been isolated by
expression cloning from rat kidney. The predicted 45K protein, which features two potential …

▪ Abstract The intrinsic electrical properties of neurons are shaped in large part by the action
of voltage-gated ion channels. Molecular cloning studies have revealed a large family of ion …

The intrinsic electrical characteristics of different types of neurons are shaped by the K+
channels they express. From among the more than 70 different K+ channel genes …

The complete amino acid sequence of a novel ryanodine receptor/calcium release channel
from rabbit brain has been deduced by cloning and sequence analysis of the EDNA. This …

The sequence of 4968 (or 4976 with an insertion) amino acids composing the ryanodine
receptor from rabbit cardiac sarcoplasmic reticulum has been deduced by cloning and …

THE glutamate receptor (GluR) channel plays a key part in brain function1, 2. Among GluR
channel subtypes, the NMDA (JV-methyl-D-aspartate) receptor channel which is highly …