Function and biogenesis of lipopolysaccharides

B Bertani, N Ruiz - Ecosal plus, 2018 - Am Soc Microbiol
The cell envelope is the first line of defense between a bacterium and the world-at-large.
Often, the initial steps that determine the outcome of chemical warfare, bacteriophage …

Outer membrane biogenesis

A Konovalova, DE Kahne… - Annual review of …, 2017 - annualreviews.org
The hallmark of gram-negative bacteria and organelles such as mitochondria and
chloroplasts is the presence of an outer membrane. In bacteria such as Escherichia coli, the …

Peptidoglycan: structure, synthesis, and regulation

S Garde, PK Chodisetti, M Reddy - EcoSal Plus, 2021 - Am Soc Microbiol
Peptidoglycan is a defining feature of the bacterial cell wall. Initially identified as a target of
the revolutionary beta-lactam antibiotics, peptidoglycan has become a subject of much …

A penicillin-binding protein inhibits selection of colistin-resistant, lipooligosaccharide-deficient Acinetobacter baumannii

JM Boll, AA Crofts, K Peters, V Cattoir… - Proceedings of the …, 2016 - National Acad Sciences
The Gram-negative bacterial outer membrane fortifies the cell against environmental toxins
including antibiotics. Unique glycolipids called lipopolysaccharide/lipooligosaccharide …

Lipid flippases for bacterial peptidoglycan biosynthesis

N Ruiz - Lipid insights, 2015 - journals.sagepub.com
The biosynthesis of cellular polysaccharides and glycoconjugates often involves lipid-linked
intermediates that need to be translocated across membranes. Essential pathways such as …

Cyclic enterobacterial common antigen maintains the outer membrane permeability barrier of Escherichia coli in a manner controlled by YhdP

AM Mitchell, T Srikumar, TJ Silhavy - MBio, 2018 - Am Soc Microbiol
Gram-negative bacteria have an outer membrane (OM) impermeable to many toxic
compounds that can be further strengthened during stress. In Enterobacteriaceae, the …

Lipopolysaccharide biosynthesis and traffic in the envelope of the pathogen Brucella abortus

C Servais, V Vassen, A Verhaeghe, N Küster… - Nature …, 2023 - nature.com
Lipopolysaccharide is essential for most Gram-negative bacteria as it is a main component
of the outer membrane. In the pathogen Brucella abortus, smooth lipopolysaccharide …

Repeat-unit elongations to produce bacterial complex long polysaccharide chains, an O-antigen perspective

Y Hong, D Hu, AD Verderosa, J Qin, M Totsika… - EcoSal …, 2023 - Am Soc Microbiol
The O-antigen, a long polysaccharide that constitutes the distal part of the outer membrane-
anchored lipopolysaccharide, is one of the critical components in the protective outer …

Vancomycin functionalization of gold nanostars for sensitive detection of foodborne pathogens through surface‐enhanced Raman scattering

S Dayalan, G Gedda, RN Li, M Zulfajri… - Journal of the …, 2022 - Wiley Online Library
In this paper, we report a sensitive surface‐enhanced Raman scattering (SERS) biosensor
for the detection of food‐borne pathogens on the basis of recognition of bacterial cells …

Divergent effects of peptidoglycan carboxypeptidase DacA on intrinsic β-lactam and vancomycin resistance

SH Park, U Choi, SH Ryu, HB Lee, JW Lee… - Microbiology …, 2022 - Am Soc Microbiol
Vancomycin and β-lactams are clinically important antibiotics that inhibit the formation of
peptidoglycan cross-links, but their binding targets are different. The binding target of …