The potential preventive and therapeutic roles of NSAIDs in prostate cancer
H Maghsoudi, F Sheikhnia, P Sitarek, N Hajmalek… - Cancers, 2023 - mdpi.com
Simple Summary Prostate cancer is a serious health problem for men around the world, and
it is often caused by inflammation in the prostate gland. The authors of this article explore …
it is often caused by inflammation in the prostate gland. The authors of this article explore …
Interplay between m6A epitranscriptome and epigenome in cancer: current knowledge and therapeutic perspectives
Chromatin has an extremely flexible structure that allows the fine regulation of gene
expression. To orchestrate this process, small chemical modifications are dynamically …
expression. To orchestrate this process, small chemical modifications are dynamically …
Niosomal formulation of mefenamic acid for enhanced cancer targeting; preparation, characterization and biodistribution study using radiolabeling technique
Background This work aimed to prepare niosomal formulations of an anticancer agent
[mefenamic acid (MEF)] to enhance its cancer targeting. 131I was utilized as a radiolabeling …
[mefenamic acid (MEF)] to enhance its cancer targeting. 131I was utilized as a radiolabeling …
NOS2 and COX-2 Co-Expression Promotes Cancer Progression: A Potential Target for Developing Agents to Prevent or Treat Highly Aggressive Breast Cancer
LL Coutinho, EL Femino, AL Gonzalez… - International Journal of …, 2024 - mdpi.com
Nitric oxide (NO) and reactive nitrogen species (RNS) exert profound biological impacts
dictated by their chemistry. Understanding their spatial distribution is essential for …
dictated by their chemistry. Understanding their spatial distribution is essential for …
Effective holistic characterization of small molecule effects using heterogeneous biological networks
The two most common reasons for attrition in therapeutic clinical trials are efficacy and
safety. We integrated heterogeneous data to create a human interactome network to …
safety. We integrated heterogeneous data to create a human interactome network to …
Mefenamic acid exhibits antitumor activity against osteosarcoma by impeding cell growth and prompting apoptosis in human osteosarcoma cells and xenograft mice …
J Ye, T Chang, X Zhang, D Wei, Y Wang - Chemico-Biological Interactions, 2024 - Elsevier
The study investigates the anticancer activity of mefenamic acid against osteosarcoma,
shedding light on its underlying mechanisms and therapeutic potential. Mefenamic acid …
shedding light on its underlying mechanisms and therapeutic potential. Mefenamic acid …
The cytotoxic activity evaluation of an arylhydrazone derivative of mefenamic acid on HEPG2 liver cancer cells and normal gingival HGF cells
T Hojatipour, S Pashapour, A Almasirad, Z Mousavi - Gene Reports, 2023 - Elsevier
Background and objective Although the anti-cancer effects of nonsteroidal anti-inflammatory
drugs have been shown in many studies, the results are still controversial. This study aimed …
drugs have been shown in many studies, the results are still controversial. This study aimed …
[PDF][PDF] The Potential Preventive and Therapeutic Roles of NSAIDs in Prostate Cancer. Cancers 2023, 15, 5435
H Maghsoudi, F Sheikhnia, P Sitarek, N Hajmalek… - 2023 - academia.edu
Prostate cancer (PC) is the second most common type of cancer and the leading cause of
death among men worldwide. Preventing the progression of cancer after treatments such as …
death among men worldwide. Preventing the progression of cancer after treatments such as …
Fenamates: Forgotten treasure for cancer treatment and prevention: Mechanisms of action, structural modification, and bright future
J Li, X Wang, H Zhang, X Hu, X Peng… - Medicinal Research … - Wiley Online Library
Fenamates as classical nonsteroidal anti‐inflammatory agents are widely used for relieving
pain. Preclinical studies and epidemiological data highlight their chemo‐preventive and …
pain. Preclinical studies and epidemiological data highlight their chemo‐preventive and …