Hippocampal sclerosis (HS) is a common pathology encountered in mesial temporal lobe
epilepsy (MTLE) as well as other epilepsy syndromes and in both surgical and post‐mortem …

For about 30% of patients with epilepsy the cause is unknown. Even in patients with a
known risk factor for epilepsy, such as ischaemic stroke, only a subpopulation of patients …

Hippocampal sclerosis (HS) is the most frequent histopathology encountered in patients with
drug‐resistant temporal lobe epilepsy (TLE). Over the past decades, various attempts have …

Objective We reviewed data on the epidemiology of epilepsy in the United States and
estimated the prevalence and incidence of drug-resistant temporal lobe epilepsy (TLE) due …

Fundamental work on the mechanisms leading to focal epileptic discharges in mesial
temporal lobe epilepsy (MTLE) often rests on the use of rodent models in which an initial …

Seizure activity in the hippocampal region strongly affects stem cell-associated plasticity in
the adult dentate gyrus. Here, we describe how seizures in rodent models of mesial …

Epilepsy is a group of chronic neurological disorders characterized by recurrent,
spontaneous, and unpredictable seizures. It is one of the most common neurological …

Our inability to adequately treat many patients with refractory epilepsy caused by focal
cortical dysplasia (FCD), surgical inaccessibility and failures are significant clinical …

Epilepsy is a frequent neurological disorder, although onset and progression of seizures
remain difficult to predict in affected patients, irrespective of their epileptogenic condition …

To clarify the anatomical organization of human memory remains a major challenge in
clinical neuroscience. Experimental data suggest dentate gyrus granule cells play a major …