Hypothermic oxygenated perfusion in liver transplantation: a meta-analysis of randomized controlled trials and matched studies

G Tang, L Zhang, L Xia, J Zhang, Z Wei… - International Journal of …, 2024 - journals.lww.com
Background: Hypothermic oxygenated machine perfusion (HOPE) is a novel organ-
preservation technology designed to optimize organ quality. However, the effects of HOPE …

Pushing the boundaries of innovation: the potential of ex vivo organ perfusion from an interdisciplinary point of view

J Iske, A Schroeter, S Knoedler… - Frontiers in …, 2023 - frontiersin.org
Ex vivo machine perfusion (EVMP) is an emerging technique for preserving explanted solid
organs with primary application in allogeneic organ transplantation. EVMP has been …

Quantitative metabolomics of tissue, perfusate, and bile from rat livers subjected to normothermic machine perfusion

C Lonati, D Dondossola, L Zizmare, M Battistin, L Wüst… - Biomedicines, 2022 - mdpi.com
Machine perfusion (MP) allows the maintenance of liver cells in a metabolically active state
ex vivo and can potentially revert metabolic perturbations caused by donor warm ischemia …

Ex Vivo Liver Machine Perfusion: Comprehensive Review of Common Animal Models

V Muth, JMGV Gassner, S Moosburner… - … Engineering Part B …, 2023 - liebertpub.com
The most common preservation technique for liver grafts is static cold storage. Due to the
organ shortage for liver transplantation (LT), extended criteria donor (ECD) allografts are …

Impact of Back-to-Base Normothermic Machine Perfusion on Complications and Costs: A Multi-Center, Real-World Risk-Matched Analysis

CJ Wehrle, M Zhang, M Khalil, A Pita, JM Esfeh… - Annals of …, 2024 - journals.lww.com
Objective: Assess cost and complication outcomes after liver transplantation (LT) using
normothermic machine perfusion (NMP) Summary Background Data: End-ischemic NMP is …

[HTML][HTML] Comprehensive approach to assessment of liver viability during normothermic machine perfusion

J Li, H Lu, J Zhang, Y Li, Q Zhao - Journal of Clinical and …, 2023 - ncbi.nlm.nih.gov
Liver transplantation is the most effective treatment of advanced liver disease, and the use of
extended criteria donor organs has broadened the source of available livers. Although …

Creating synthetic populations in transplantation: A Bayesian approach enabling simulation without registry re-sampling

PR Gunsalus, J Rose, CJ Lehr, M Valapour, JE Dalton - Plos one, 2024 - journals.plos.org
Computer simulation has played a pivotal role in analyzing alternative organ allocation
strategies in transplantation. The current approach to producing cohorts of organ donors and …

The Role of Normothermic Machine Perfusion in Extended Criteria Donor Grafts: A New Direction in Liver Graft Assessment and Preservation

D Malkawi, K Savsani, A Alfonso, SD Lee, N James… - Livers, 2023 - mdpi.com
Despite improvements in short-term and long-term outcomes of liver transplant patients, the
discrepancy between the number of available livers and transplant candidates continues to …

The need to update endpoints and outcome analysis in the rapidly changing field of liver transplantation

M Fodor, H Zoller, R Oberhuber, R Sucher… - …, 2022 - journals.lww.com
Liver transplantation (LT) survival rates have continued to improve over the last decades,
mostly due to the reduction of mortality early after transplantation. The advancement is …

Combined Liver Transplant and Cardiac Surgery: Long-Term Outcomes and Predictors of Success

CJ Wehrle, A Schlegel, M Khalil, D Rotroff… - Annals of …, 2023 - journals.lww.com
Objective: We aim to report our institutional outcomes of single-staged combined liver
transplantation (LT) and cardiac surgery (CS). Summary Background Data: Concurrent LT …