EFNS guidelines on the clinical management of amyotrophic lateral sclerosis (MALS)–revised report of an EFNS task force

EFNS Task Force on Diagnosis and … - European journal of …, 2012 - Wiley Online Library
Background: The evidence base for the diagnosis and management of amyotrophic lateral
sclerosis (ALS) is weak. Objectives: To provide evidence‐based or expert recommendations …

Supportive and symptomatic management of amyotrophic lateral sclerosis

EV Hobson, CJ McDermott - Nature Reviews Neurology, 2016 - nature.com
The main aims in the care of individuals with amyotrophic lateral sclerosis (ALS) are to
minimize morbidity and maximize quality of life. Although no cure exists for ALS, supportive …

Pain in amyotrophic lateral sclerosis

A Chiò, G Mora, G Lauria - The Lancet Neurology, 2017 - thelancet.com
Pain is a largely neglected symptom in patients with amyotrophic lateral sclerosis (ALS)
although it is reported by most of these patients. It occurs at all stages of the disease and can …

Polyanalgesic Consensus Conference 2012: recommendations for the management of pain by intrathecal (intraspinal) drug delivery: report of an interdisciplinary …

TR Deer, J Prager, R Levy, J Rathmell… - … : Technology at the …, 2012 - Elsevier
Introduction The use of intrathecal (IT) infusion of analgesic medications to treat patients with
chronic refractory pain has increased since its inception in the 1980s, and the need for …

Canadian best practice recommendations for the management of amyotrophic lateral sclerosis

C Shoesmith, A Abrahao, T Benstead, M Chum… - Cmaj, 2020 - Can Med Assoc
The care and management of patients with ALS should always be patient focused, with
attention to holistic and emotional aspects of well-being. It is the patient who ultimately …

A systematic review of non-motor symptom evaluation in clinical trials for amyotrophic lateral sclerosis

E Beswick, D Forbes, Z Hassan, C Wong, J Newton… - Journal of …, 2022 - Springer
Background Amyotrophic lateral sclerosis (ALS) is increasingly recognised as a multi-
system disorder, presenting with common and impactful non-motor symptoms, such as …

Care management in amyotrophic lateral sclerosis

MH Soriani, C Desnuelle - Revue neurologique, 2017 - Elsevier
Amyotrophic lateral sclerosis (ALS) is a relentlessly progressive and fatal
neurodegenerative disease characterized by progressive weakness of voluntary muscles of …

Pain in neurodegenerative disease: current knowledge and future perspectives

M de Tommaso, L Arendt-Nielsen, R Defrin… - Behavioural …, 2016 - Wiley Online Library
Neurodegenerative diseases are going to increase as the life expectancy is getting longer.
The management of neurodegenerative diseases such as Alzheimer's disease (AD) and …

Amyotrophic lateral sclerosis and palliative care: where we are, and the road ahead

LJ Blackhall - Muscle & nerve, 2012 - Wiley Online Library
Patients with amyotrophic lateral sclerosis (ALS) have high symptom burdens, including
pain, fatigue, dyspnea, and sialorrhea, and they must make difficult decisions about the use …

Nonmotor symptoms in amyotrophic lateral sclerosis: a systematic review

T Fang, F Jozsa, A Al-Chalabi - International review of neurobiology, 2017 - Elsevier
Background: ALS is a progressive neurodegenerative disease with no curative treatment.
Nonmotor symptoms presenting in ALS may cause significant distress, worsen prognosis …