[HTML][HTML] Arachidonic acid: physiological roles and potential health benefits–a review
It is time to shift the arachidonic acid (ARA) paradigm from a harm-generating molecule to its
status of polyunsaturated fatty acid essential for normal health. ARA is an integral constituent …
status of polyunsaturated fatty acid essential for normal health. ARA is an integral constituent …
The dark side of C5a in sepsis
PA Ward - Nature Reviews Immunology, 2004 - nature.com
Sepsis is a major clinical problem for which therapeutic interventions have been largely
unsuccessful, in spite of promising strategies that were successful in animals, especially …
unsuccessful, in spite of promising strategies that were successful in animals, especially …
[HTML][HTML] Oral administration of oleic or linoleic acid accelerates the inflammatory phase of wound healing
HG Rodrigues, MAR Vinolo, J Magdalon… - Journal of Investigative …, 2012 - Elsevier
The effects of oral ingestion of oleic (OLA) and linoleic (LNA) acids on wound healing in rats
were investigated. LNA increased the influx of inflammatory cells, the concentration of …
were investigated. LNA increased the influx of inflammatory cells, the concentration of …
[HTML][HTML] Targeting lipid metabolism of macrophages: A new strategy for tumor therapy
N Shao, H Qiu, J Liu, D Xiao, J Zhao, C Chen… - Journal of Advanced …, 2024 - Elsevier
Background Lipid metabolism has been implicated in a variety of normal cellular processes
and strongly related to the development of multiple diseases, including tumor. Tumor …
and strongly related to the development of multiple diseases, including tumor. Tumor …
Rheumatoid arthritis: the role of reactive oxygen species in disease development and therapeutic strategies
KA Gelderman, M Hultqvist, LM Olsson… - Antioxidants & Redox …, 2007 - liebertpub.com
Autoimmune diseases such as rheumatoid arthritis (RA) are chronic diseases that cannot be
prevented or cured. If the pathologic basis of such diseases would be known, it might be …
prevented or cured. If the pathologic basis of such diseases would be known, it might be …
Free Fatty Acids and Methyl Jasmonate Trigger Defense Reactions in Laminaria digitata
FC Küpper, E Gaquerel, A Cosse, F Adas… - Plant and Cell …, 2009 - academic.oup.com
Arachidonic acid, linolenic acid and methyl jasmonate (MeJA) were found to be strong
triggers of an oxidative burst in the kelp Laminaria digitata. These findings constitute the first …
triggers of an oxidative burst in the kelp Laminaria digitata. These findings constitute the first …
[HTML][HTML] Phosphoproteomics identify arachidonic-acid-regulated signal transduction pathways modulating macrophage functions with implications for ovarian cancer
R Dietze, MK Hammoud, M Gómez-Serrano… - Theranostics, 2021 - ncbi.nlm.nih.gov
Arachidonic acid (AA) is a polyunsaturated fatty acid present at high concentrations in the
ovarian cancer (OC) microenvironment and associated with a poor clinical outcome. In the …
ovarian cancer (OC) microenvironment and associated with a poor clinical outcome. In the …
Comparative toxicity of fatty acids on a macrophage cell line (J774)
T Martins de Lima, MF Cury-Boaventura… - Clinical …, 2006 - portlandpress.com
In the present study, the cytotoxicity of palmitic, stearic, oleic, linoleic, arachidonic,
docosahexaenoic and eicosapentaenoic acids on a macrophage cell line (J774) was …
docosahexaenoic and eicosapentaenoic acids on a macrophage cell line (J774) was …
Arachidonic acid, a clinically adverse mediator in the ovarian cancer microenvironment, impairs JAK‐STAT signaling in macrophages by perturbing lipid raft structures
MK Hammoud, R Dietze, J Pesek… - Molecular …, 2022 - Wiley Online Library
Survival of ovarian carcinoma is associated with the abundance of immunosuppressed
CD163highCD206high tumor‐associated macrophages (TAMs) and high levels of …
CD163highCD206high tumor‐associated macrophages (TAMs) and high levels of …
Isolation of ellagic acid from the aqueous extract of the roots of Decalepis hamiltonii: Antioxidant activity and cytoprotective effect
A Srivastava, LJM Rao, T Shivanandappa - Food chemistry, 2007 - Elsevier
Roots of Decalepis hamiltonii are consumed as pickles and as a beverage and are believed
to possess health-promoting properties. Roots of D. hamiltonii exhibit antioxidant properties …
to possess health-promoting properties. Roots of D. hamiltonii exhibit antioxidant properties …