Distinct host-response signatures in circulatory shock: a narrative review

S Soussi, C Dos Santos, JC Jentzer, A Mebazaa… - Intensive Care Medicine …, 2023 - Springer
Circulatory shock is defined syndromically as hypotension associated with tissue
hypoperfusion and often subcategorized according to hemodynamic profile (eg, distributive …

Increased plasma hyaluronan levels are associated with acute traumatic coagulopathy

SC Walker, RP Richter, L Zheng, AR Ashtekar… - Shock, 2022 - journals.lww.com
Methods: We performed a secondary analysis of prospectively collected data from a recent
study in which trauma patients (> 18 years) admitted to our Level I trauma center with an …

Serum angiopoietin-2/angiopoietin-1 ratio is associated with cardiovascular and all-cause mortality in peritoneal dialysis patients: a prospective cohort study

H Li, Q Song, X Su, Y Shen, H Yan, Z Yu, Z Li… - Renal …, 2024 - Taylor & Francis
Introduction Our objective was to examine the factors associated with the serum
angiopoietin-2/angiopoietin-1 (Angpt-2/Angpt-1) ratio in peritoneal dialysis (PD) patients …

Trauma promotes heparan sulfate modifications and cleavage that disrupt homeostatic gene expression in microvascular endothelial cells

RP Richter, JD Odum, C Margaroli… - Frontiers in Cell and …, 2024 - frontiersin.org
Introduction: Heparan sulfate (HS) in the vascular endothelial glycocalyx (eGC) is a critical
regulator of blood vessel homeostasis. Trauma results in HS shedding from the eGC, but the …

Endotheliopathy is associated with a 24-hour fibrinolysis phenotype described by low TEG lysis and high D-dimer after trauma: a secondary analysis of the PROPPR …

RP Richter, DM Joiner, RL Griffin, JO Jansen… - Annals of Surgery …, 2022 - journals.lww.com
Objectives: Determine associations between biomarkers of endotheliopathy, 24-hour
fibrinolysis phenotypes and clinical outcomes after trauma. Background: The vascular …

Histone deacetylase-6 modulates the effects of 4° C platelets on vascular endothelial permeability

B Miyazawa, A Trivedi, L Vivona, M Lin… - Blood …, 2023 - ashpublications.org
Platelets (PLTs) stored at 4° C exhibit equivalent or superior hemostatic function compared
with 22° C PLTs, but have shorter circulation times and a decreased ability to modulate …

[HTML][HTML] Гиповолемический шок у взрослых. Клинические рекомендации Общероссийской общественной организации «Федерация анестезиологов и …

ИБ Заболотских, ЕВ Григорьев… - … терапии имени АИ …, 2024 - cyberleninka.ru
В статье представлены основные положения клинических рекомендаций по
диагностике и терапии гиповолемического шока у взрослых, утвержденных …

Syndecan-1 and thrombomodulin are early biomarkers for development of endotheliopathy in trauma and hemorrhagic shock

TC Chance, MA Meledeo, AP Cap, DN Darlington… - bioRxiv, 2023 - biorxiv.org
The causes of endotheliopathy are multifactorial and trauma dependent, and the temporal
mechanistic link that it has with acute traumatic coagulopathy (ATC) has yet to be fully …