Microenvironment imbalance of spinal cord injury

B Fan, Z Wei, X Yao, G Shi, X Cheng… - Cell …, 2018 - journals.sagepub.com
Spinal cord injury (SCI), for which there currently is no cure, is a heavy burden on patient
physiology and psychology. The microenvironment of the injured spinal cord is complicated …

Natural polymer‐derived bioscaffolds for peripheral nerve regeneration

H Zhang, J Guo, Y Wang, L Shang… - Advanced Functional …, 2022 - Wiley Online Library
In recent decades, artificial nerve scaffolds have become a promising substitute for
peripheral nerve repair. Considerable efforts have been devoted to improving the …

Application of conductive PPy/SF composite scaffold and electrical stimulation for neural tissue engineering

Y Zhao, Y Liang, S Ding, K Zhang, H Mao, Y Yang - Biomaterials, 2020 - Elsevier
Electrical stimulation (ES) with conductive polymers can dramatically enhance neurite
outgrowth and promote neural regeneration. However, besides ES, the practical …

Overlapping transcriptional programs promote survival and axonal regeneration of injured retinal ganglion cells

A Jacobi, NM Tran, W Yan, I Benhar, F Tian, R Schaffer… - Neuron, 2022 - cell.com
Injured neurons in the adult mammalian central nervous system often die and seldom
regenerate axons. To uncover transcriptional pathways that could ameliorate these …

Immune cytokines and their receptors in inflammatory pain

AD Cook, AD Christensen, D Tewari, SB McMahon… - Trends in …, 2018 - cell.com
There is burgeoning interest in the interaction between the immune and nervous systems.
Pain is mediated by primary sensory neurons (nociceptors) that can respond to a variety of …

Schwann cell interactions with axons and microvessels in diabetic neuropathy

NP Gonçalves, CB Vægter, H Andersen… - Nature Reviews …, 2017 - nature.com
The prevalence of diabetes worldwide is at pandemic levels, with the number of patients
increasing by 5% annually. The most common complication of diabetes is peripheral …

The role of BDNF in peripheral nerve regeneration: activity-dependent treatments and Val66Met

CE McGregor, AW English - Frontiers in cellular neuroscience, 2019 - frontiersin.org
Despite the ability of peripheral nerves to spontaneously regenerate after injury, recovery is
generally very poor. The neurotrophins have emerged as an important modulator of axon …

[HTML][HTML] Self-assembling peptide hydrogels functionalized with LN-and BDNF-mimicking epitopes synergistically enhance peripheral nerve regeneration

S Yang, C Wang, J Zhu, C Lu, H Li, F Chen, J Lu… - Theranostics, 2020 - ncbi.nlm.nih.gov
The regenerative capacity of the peripheral nervous system is closely related to the role that
Schwann cells (SCs) play in construction of the basement membrane containing multiple …

The effect of electrical stimulation on nerve regeneration following peripheral nerve injury

L Juckett, TM Saffari, B Ormseth, JL Senger, AM Moore - Biomolecules, 2022 - mdpi.com
Peripheral nerve injuries (PNI) are common and often result in lifelong disability. The
peripheral nervous system has an inherent ability to regenerate following injury, yet …

What causes eye pain?

C Belmonte, MC Acosta, J Merayo-Lloves… - Current ophthalmology …, 2015 - Springer
Eye pain is an unpleasant sensory and emotional experience including sensory-
discriminative, emotional, cognitive, and behavioral components and supported by distinct …