Advanced cell culture techniques for cancer drug discovery

CJ Lovitt, TB Shelper, VM Avery - Biology, 2014 - mdpi.com
Human cancer cell lines are an integral part of drug discovery practices. However, modeling
the complexity of cancer utilizing these cell lines on standard plastic substrata, does not …

Human-induced evolution caused by unnatural selection through harvest of wild animals

FW Allendorf, JJ Hard - Proceedings of the National …, 2009 - National Acad Sciences
Human harvest of phenotypically desirable animals from wild populations imposes selection
that can reduce the frequencies of those desirable phenotypes. Hunting and fishing contrast …

BOFFFFs: on the importance of conserving old-growth age structure in fishery populations

MA Hixon, DW Johnson… - ICES Journal of Marine …, 2014 - academic.oup.com
The value of big old fat fecund female fish (BOFFFFs) in fostering stock productivity and
stability has long been underappreciated by conventional fisheries science and …

Understanding and monitoring the consequences of human impacts on intraspecific variation

M Mimura, T Yahara, DP Faith… - Evolutionary …, 2017 - Wiley Online Library
Intraspecific variation is a major component of biodiversity, yet it has received relatively little
attention from governmental and nongovernmental organizations, especially with regard to …

Fishing‐induced evolution of growth: Concepts, mechanisms and the empirical evidence

K Enberg, C Jørgensen, ES Dunlop, Ø Varpe… - Marine …, 2012 - Wiley Online Library
The interest in fishing‐induced life‐history evolution has been growing in the last decade, in
part because of the increasing number of studies suggesting evolutionary changes in life …

Contrasting genomic shifts underlie parallel phenotypic evolution in response to fishing

NO Therkildsen, AP Wilder, DO Conover, SB Munch… - Science, 2019 - science.org
Humans cause widespread evolutionary change in nature, but we still know little about the
genomic basis of rapid adaptation in the Anthropocene. We tracked genomic changes …

Potential environmental impacts of recreational fishing on marine fish stocks and ecosystems

WC Lewin, MS Weltersbach, K Ferter… - Reviews in Fisheries …, 2019 - Taylor & Francis
Marine recreational fishing (MRF) is a popular activity that involves millions of people
worldwide. While the impacts of recreational fishing on freshwater ecosystems received …

The evolutionary legacy of size‐selective harvesting extends from genes to populations

S Uusi‐Heikkilä, AR Whiteley… - Evolutionary …, 2015 - Wiley Online Library
Size‐selective harvesting is assumed to alter life histories of exploited fish populations,
thereby negatively affecting population productivity, recovery, and yield. However …

Harmonizing recreational fisheries and conservation objectives for aquatic biodiversity in inland waters

IG Cowx, R Arlinghaus, SJ Cooke - Journal of Fish Biology, 2010 - Wiley Online Library
The importance of recreational fisheries to local and national economies, and as a generator
of immense social welfare throughout the developed world, is well established …

Implications of fisheries‐induced evolution for stock rebuilding and recovery

K Enberg, C Jørgensen, ES Dunlop… - Evolutionary …, 2009 - Wiley Online Library
Worldwide depletion of fish stocks has led fisheries managers to become increasingly
concerned about rebuilding and recovery planning. To succeed, factors affecting recovery …