Advanced cell culture techniques for cancer drug discovery
CJ Lovitt, TB Shelper, VM Avery - Biology, 2014 - mdpi.com
Human cancer cell lines are an integral part of drug discovery practices. However, modeling
the complexity of cancer utilizing these cell lines on standard plastic substrata, does not …
the complexity of cancer utilizing these cell lines on standard plastic substrata, does not …
Human-induced evolution caused by unnatural selection through harvest of wild animals
FW Allendorf, JJ Hard - Proceedings of the National …, 2009 - National Acad Sciences
Human harvest of phenotypically desirable animals from wild populations imposes selection
that can reduce the frequencies of those desirable phenotypes. Hunting and fishing contrast …
that can reduce the frequencies of those desirable phenotypes. Hunting and fishing contrast …
BOFFFFs: on the importance of conserving old-growth age structure in fishery populations
MA Hixon, DW Johnson… - ICES Journal of Marine …, 2014 - academic.oup.com
The value of big old fat fecund female fish (BOFFFFs) in fostering stock productivity and
stability has long been underappreciated by conventional fisheries science and …
stability has long been underappreciated by conventional fisheries science and …
Understanding and monitoring the consequences of human impacts on intraspecific variation
M Mimura, T Yahara, DP Faith… - Evolutionary …, 2017 - Wiley Online Library
Intraspecific variation is a major component of biodiversity, yet it has received relatively little
attention from governmental and nongovernmental organizations, especially with regard to …
attention from governmental and nongovernmental organizations, especially with regard to …
Fishing‐induced evolution of growth: Concepts, mechanisms and the empirical evidence
The interest in fishing‐induced life‐history evolution has been growing in the last decade, in
part because of the increasing number of studies suggesting evolutionary changes in life …
part because of the increasing number of studies suggesting evolutionary changes in life …
Contrasting genomic shifts underlie parallel phenotypic evolution in response to fishing
Humans cause widespread evolutionary change in nature, but we still know little about the
genomic basis of rapid adaptation in the Anthropocene. We tracked genomic changes …
genomic basis of rapid adaptation in the Anthropocene. We tracked genomic changes …
Potential environmental impacts of recreational fishing on marine fish stocks and ecosystems
Marine recreational fishing (MRF) is a popular activity that involves millions of people
worldwide. While the impacts of recreational fishing on freshwater ecosystems received …
worldwide. While the impacts of recreational fishing on freshwater ecosystems received …
The evolutionary legacy of size‐selective harvesting extends from genes to populations
S Uusi‐Heikkilä, AR Whiteley… - Evolutionary …, 2015 - Wiley Online Library
Size‐selective harvesting is assumed to alter life histories of exploited fish populations,
thereby negatively affecting population productivity, recovery, and yield. However …
thereby negatively affecting population productivity, recovery, and yield. However …
Harmonizing recreational fisheries and conservation objectives for aquatic biodiversity in inland waters
The importance of recreational fisheries to local and national economies, and as a generator
of immense social welfare throughout the developed world, is well established …
of immense social welfare throughout the developed world, is well established …
Implications of fisheries‐induced evolution for stock rebuilding and recovery
Worldwide depletion of fish stocks has led fisheries managers to become increasingly
concerned about rebuilding and recovery planning. To succeed, factors affecting recovery …
concerned about rebuilding and recovery planning. To succeed, factors affecting recovery …