ImmunoPET: concept, design, and applications

W Wei, ZT Rosenkrans, J Liu, G Huang, QY Luo… - Chemical …, 2020 - ACS Publications
Immuno-positron emission tomography (immunoPET) is a paradigm-shifting molecular
imaging modality combining the superior targeting specificity of monoclonal antibody (mAb) …

Radioactive transition metals for imaging and therapy

E Boros, AB Packard - Chemical reviews, 2018 - ACS Publications
Nuclear medicine is composed of two complementary areas, imaging and therapy. Positron
emission tomography (PET) and single-photon imaging, including single-photon emission …

New developments in the production of theranostic pairs of radionuclides

SM Qaim, B Scholten, B Neumaier - Journal of Radioanalytical and …, 2018 - Springer
A brief historical background of the development of the theranostic approach in nuclear
medicine is given and seven theranostic pairs of radionuclides, namely 44g Sc/47 Sc, 64 …

Cyclotron-based production of 68Ga, [68Ga]GaCl3, and [68Ga]Ga-PSMA-11 from a liquid target

ME Rodnick, C Sollert, D Stark, M Clark… - EJNMMI …, 2020 - Springer
Purpose To optimize the direct production of 68 Ga on a cyclotron, via the 68 Zn (p, n) 68 Ga
reaction using a liquid cyclotron target. We Investigated the yield of cyclotron-produced 68 …

Production of novel diagnostic radionuclides in small medical cyclotrons

MA Synowiecki, LR Perk, JFW Nijsen - EJNMMI radiopharmacy and …, 2018 - Springer
The global network of cyclotrons has expanded rapidly over the last decade. The bulk of its
industrial potential is composed of small medical cyclotrons with a proton energy below 20 …

Theranostic radionuclides: recent advances in production methodologies

SM Qaim - Journal of radioanalytical and nuclear chemistry, 2019 - Springer
Various concepts involved in the quantification of radiation dose while following the
theranostic approach in nuclear medicine are outlined. The availability of the relevant …

Automated GMP compliant production of [18F]AlF-NOTA-octreotide

T Tshibangu, C Cawthorne, K Serdons… - EJNMMI radiopharmacy …, 2020 - Springer
Background Gallium-68 labeled synthetic somatostatin analogs for PET/CT imaging are the
current gold standard for somatostatin receptor imaging in neuroendocrine tumor patients …

Taking cyclotron 68Ga production to the next level: Expeditious solid target production of 68Ga for preparation of radiotracers

BJB Nelson, J Wilson, S Richter, MJM Duke… - Nuclear Medicine and …, 2020 - Elsevier
Introduction Gallium-68 is an important radionuclide for positron emission tomography (PET)
with steadily increasing applications of 68 Ga-based radiopharmaceuticals for clinical use …

Production of radiometals in liquid targets

SJC Do Carmo, PJH Scott, F Alves - EJNMMI Radiopharmacy and …, 2020 - Springer
Over the last several years, the use of radiometals has gained increasing relevance in
supporting the continuous development of new, complementary and more specific biological …

The current status of the production and supply of gallium-68

K Kumar - Cancer biotherapy & radiopharmaceuticals, 2020 - liebertpub.com
Gallium-68 (68Ga) is an important radionuclide due to its successful use in the clinic.
Currently, 68Ga is produced and supplied by using germanium-68/Gallium-68 (68Ge/68Ga) …