Bacteriophages as therapeutic and diagnostic vehicles in cancer

V Foglizzo, S Marchiò - Pharmaceuticals, 2021 - mdpi.com
Evolution of nanomedicine is the re-design of synthetic and biological carriers to implement
novel theranostic platforms. In recent years, bacteriophage research favors this process …

Recent advances in applying nanotechnologies for cancer immunotherapy

R Mahjub, S Jatana, SE Lee, Z Qin, G Pauli… - Journal of controlled …, 2018 - Elsevier
Cancer immunotherapy aimed at boosting cancer-specific immunoresponses to eradicate
tumor cells has evolved as a new treatment modality. Nanoparticles incorporating antigens …

Engineered phage-based cancer vaccines: current advances and future directions

M Ragothaman, SY Yoo - Vaccines, 2023 - mdpi.com
Bacteriophages have emerged as versatile tools in the field of bioengineering, with
enormous potential in tissue engineering, vaccine development, and immunotherapy. The …

Combination of the toll like receptor agonist and α-Galactosylceramide as an efficient adjuvant for cancer vaccine

F Gableh, M Saeidi, S Hemati, K Hamdi… - Journal of biomedical …, 2016 - Springer
Background DNA vaccines have emerged as an attractive approach for the generation of
cytotoxic T lymphocytes (CTL). In our previous study, we found That Toll like receptor (TLR) …

Antitumor effect of therapeutic HPV DNA vaccines with chitosan-based nanodelivery systems

A Tahamtan, A Ghaemi, A Gorji, HR Kalhor… - Journal of biomedical …, 2014 - Springer
Background Cervical cancer is the second-most-common cause of malignancies in women
worldwide, and the oncogenic activity of the human papilloma virus types (HPV) E7 protein …

Comparing the effect of Toll-like receptor agonist adjuvants on the efficiency of a DNA vaccine

A Sajadian, A Tabarraei, H Soleimanjahi, F Fotouhi… - Archives of …, 2014 - Springer
We have investigated whether poly (I: C) Toll-like receptor 3 (TLR3) and resiquimod Toll-like
receptor 7 (TLR7) agonists can serve as vaccine adjuvants and promote the efficiency of …

Genistein induces a protective immunomodulatory effect in a mouse model of cervical cancer

A Ghasemi, H Soleimanjahi, S Razeghi… - Iranian Journal of …, 2012 - iji.sums.ac.ir
Background: Genistein (GEN), a naturally occurring flavonoid present in soy bean, has
attracted scientific interest for its possible benefits in cancer. Objective: The potential …

Bacteriophages as nanocarriers for targeted drug delivery and enhanced therapeutic effects

SC Emencheta, AL Onugwu, CF Kalu, PN Ezinkwo… - Materials …, 2024 - pubs.rsc.org
The effective delivery of therapeutic agents is as important as the active therapeutic agent
because it may make or mar the outcome. Traditional/conventional drug delivery systems …

Interleukin-12 as a genetic adjuvant enhances hepatitis C virus NS3 DNA vaccine immunogenicity

M Naderi, A Saeedi, A Moradi, M Kleshadi… - Virologica Sinica, 2013 - Springer
Hepatitis C virus (HCV) chronic infection is a worldwide health problem, and numerous
efforts have been invested to develop novel vaccines. An efficient vaccine requires broad …

[HTML][HTML] Recent Advances and Mechanisms of Phage-Based Therapies in Cancer Treatment

VY Ooi, TY Yeh - International Journal of Molecular Sciences, 2024 - mdpi.com
The increasing interest in bacteriophage technology has prompted its novel applications to
treat different medical conditions, most interestingly cancer. Due to their high specificity …