Control of cell proliferation by neurotransmitters in the developing vertebrate retina
RAP Martins, RA Pearson - Brain research, 2008 - Elsevier
In the developing vertebrate retina, precise coordination of retinal progenitor cell
proliferation and cell-cycle exit is essential for the formation of a functionally mature retina …
proliferation and cell-cycle exit is essential for the formation of a functionally mature retina …
5‐HT receptors on interstitial cells of Cajal, smooth muscle and enteric nerves
MM Wouters, G Farrugia… - Neurogastroenterology & …, 2007 - Wiley Online Library
The majority of the body's serotonin (5‐HT) is produced by the gastrointestinal tract. 5‐HT
has several functions in the gastrointestinal tract. 5‐HT is a paracrine signalling molecule …
has several functions in the gastrointestinal tract. 5‐HT is a paracrine signalling molecule …
Altered serotonin physiology in human breast cancers favors paradoxical growth and cell survival
VP Pai, AM Marshall, LL Hernandez, AR Buckley… - Breast cancer …, 2009 - Springer
Introduction The breast microenvironment can either retard or accelerate the events
associated with progression of latent cancers. However, the actions of local physiological …
associated with progression of latent cancers. However, the actions of local physiological …
Exogenous serotonin regulates proliferation of interstitial cells of Cajal in mouse jejunum through 5-HT2B receptors
MM Wouters, SJ Gibbons, JL Roeder, M Distad, Y Ou… - Gastroenterology, 2007 - Elsevier
Background & Aims: Interstitial cells of Cajal (ICC) are required for normal gastrointestinal
motility. Loss of ICC is associated with several motility disorders. The mechanisms …
motility. Loss of ICC is associated with several motility disorders. The mechanisms …
The central serotonin2B receptor as a new pharmacological target for the treatment of dopamine-related neuropsychiatric disorders: Rationale and current status of …
C Devroye, A Cathala, PV Piazza… - Pharmacology & …, 2018 - Elsevier
Abstract The serotonin 2B receptor (5-HT 2B R), which was first cloned and characterized in
the rat stomach fundus, is the most recent addition to the 5-HT 2 R family. While its …
the rat stomach fundus, is the most recent addition to the 5-HT 2 R family. While its …
Computational methods for the identification of molecular targets of toxic food additives. Butylated hydroxytoluene as a case study
V Tortosa, V Pietropaolo, V Brandi, G Macari… - Molecules, 2020 - mdpi.com
Butylated hydroxytoluene (BHT) is one of the most commonly used synthetic antioxidants in
food, cosmetic, pharmaceutical and petrochemical products. BHT is considered safe for …
food, cosmetic, pharmaceutical and petrochemical products. BHT is considered safe for …
Continued growth and circuit building in the anamniote visual system
Fish and amphibia are capable of lifelong growth and regeneration. The two core
components of their visual system, the retina and tectum both maintain small populations of …
components of their visual system, the retina and tectum both maintain small populations of …
Growth factors improve neurogenesis and outcome after focal cerebral ischemia
RR Leker, V Lasri, D Chernoguz - Journal of Neural Transmission, 2009 - Springer
Stem cells have been proposed as a new form of cell-based therapy in a variety of disorders,
including acute and degenerative brain diseases. Endogenous neural stem cells (eNSC) …
including acute and degenerative brain diseases. Endogenous neural stem cells (eNSC) …
Serotonin 2B receptor signaling is required for craniofacial morphogenesis and jaw joint formation in Xenopus
E Reisoli, S De Lucchini, I Nardi, M Ori - Development, 2010 - journals.biologists.com
Serotonin (5-HT) is a neuromodulator that plays many different roles in adult and embryonic
life. Among the 5-HT receptors, 5-HT2B is one of the key mediators of 5-HT functions during …
life. Among the 5-HT receptors, 5-HT2B is one of the key mediators of 5-HT functions during …
Serotonin strengthens a developing glutamatergic synapse through a PI3K-dependent mechanism
UG Udoh, JR Bruno, PO Osborn… - Journal of …, 2024 - Soc Neuroscience
It is well established that, during neural circuit development, glutamatergic synapses
become strengthened via NMDA receptor (NMDAR)-dependent upregulation of AMPA …
become strengthened via NMDA receptor (NMDAR)-dependent upregulation of AMPA …