Control of cell proliferation by neurotransmitters in the developing vertebrate retina

RAP Martins, RA Pearson - Brain research, 2008 - Elsevier
In the developing vertebrate retina, precise coordination of retinal progenitor cell
proliferation and cell-cycle exit is essential for the formation of a functionally mature retina …

5‐HT receptors on interstitial cells of Cajal, smooth muscle and enteric nerves

MM Wouters, G Farrugia… - Neurogastroenterology & …, 2007 - Wiley Online Library
The majority of the body's serotonin (5‐HT) is produced by the gastrointestinal tract. 5‐HT
has several functions in the gastrointestinal tract. 5‐HT is a paracrine signalling molecule …

Altered serotonin physiology in human breast cancers favors paradoxical growth and cell survival

VP Pai, AM Marshall, LL Hernandez, AR Buckley… - Breast cancer …, 2009 - Springer
Introduction The breast microenvironment can either retard or accelerate the events
associated with progression of latent cancers. However, the actions of local physiological …

Exogenous serotonin regulates proliferation of interstitial cells of Cajal in mouse jejunum through 5-HT2B receptors

MM Wouters, SJ Gibbons, JL Roeder, M Distad, Y Ou… - Gastroenterology, 2007 - Elsevier
Background & Aims: Interstitial cells of Cajal (ICC) are required for normal gastrointestinal
motility. Loss of ICC is associated with several motility disorders. The mechanisms …

The central serotonin2B receptor as a new pharmacological target for the treatment of dopamine-related neuropsychiatric disorders: Rationale and current status of …

C Devroye, A Cathala, PV Piazza… - Pharmacology & …, 2018 - Elsevier
Abstract The serotonin 2B receptor (5-HT 2B R), which was first cloned and characterized in
the rat stomach fundus, is the most recent addition to the 5-HT 2 R family. While its …

Computational methods for the identification of molecular targets of toxic food additives. Butylated hydroxytoluene as a case study

V Tortosa, V Pietropaolo, V Brandi, G Macari… - Molecules, 2020 - mdpi.com
Butylated hydroxytoluene (BHT) is one of the most commonly used synthetic antioxidants in
food, cosmetic, pharmaceutical and petrochemical products. BHT is considered safe for …

Continued growth and circuit building in the anamniote visual system

KL Cerveny, M Varga, SW Wilson - Developmental …, 2012 - Wiley Online Library
Fish and amphibia are capable of lifelong growth and regeneration. The two core
components of their visual system, the retina and tectum both maintain small populations of …

Growth factors improve neurogenesis and outcome after focal cerebral ischemia

RR Leker, V Lasri, D Chernoguz - Journal of Neural Transmission, 2009 - Springer
Stem cells have been proposed as a new form of cell-based therapy in a variety of disorders,
including acute and degenerative brain diseases. Endogenous neural stem cells (eNSC) …

Serotonin 2B receptor signaling is required for craniofacial morphogenesis and jaw joint formation in Xenopus

E Reisoli, S De Lucchini, I Nardi, M Ori - Development, 2010 - journals.biologists.com
Serotonin (5-HT) is a neuromodulator that plays many different roles in adult and embryonic
life. Among the 5-HT receptors, 5-HT2B is one of the key mediators of 5-HT functions during …

Serotonin strengthens a developing glutamatergic synapse through a PI3K-dependent mechanism

UG Udoh, JR Bruno, PO Osborn… - Journal of …, 2024 - Soc Neuroscience
It is well established that, during neural circuit development, glutamatergic synapses
become strengthened via NMDA receptor (NMDAR)-dependent upregulation of AMPA …