The current trend of peripheral nerve tissue engineering is the design of advanced nerve
guidance channels (NGCs) acting as physical guidance for regeneration of nerves across …

Surgical repair of severe peripheral nerve injuries represents not only a pressing medical
need, but also a great clinical challenge. Autologous nerve grafting remains a golden …

Peripheral nerve injuries (PNIs) are the most common injury types to affect the nervous
system. Restoration of nerve function after PNI is a challenging medical issue. Extended …

Commercial nerve guidance conduits (NGCs) for repair of peripheral nerve discontinuities
are of little use in gaps larger than 30 mm, and for smaller gaps they often fail to compete …

Damage to the peripheral nervous system is surprisingly common and occurs primarily from
trauma or a complication of surgery. Although recovery of nerve function occurs in many mild …

Artificial nerve guide conduits have the advantage over autografts in terms of their
availability and ease of fabrication. However, clinical outcomes associated with the use of …

Peripheral nerve injury treatment is a relevant problem because of nerve lesion high
incidence and because of unsatisfactory regeneration after severe injuries, thus resulting in …

Scaffolds with inner fillers that convey directional guidance cues represent promising
candidates for nerve repair. However, incorrect positioning or non-uniform distribution of …

Bridging critical‐sized defects in peripheral nerves to achieve functional recovery is a
challenge for orthopedic and hand surgeons. Inadequate regeneration of peripheral nerve …

Effective nerve regeneration and functional recovery subsequent to peripheral nerve injury
is still a clinical challenge. Autologous nerve graft transplantation is a feasible treatment in …