Factor XIII (FXIII) is a multifunctional pro-γ-transglutaminase that, in addition to its well-
known role in hemostasis, has a crucial role in angiogenesis, maintenance of pregnancy …

Factor XIII deficiency (FXIIID) is a rare bleeding disorder with an estimated prevalence of 1 in
2-million population worldwide. In Iran, a Middle Eastern country with a high rate of …

Factor XIII (FXIII) deficiency is a rare hemorrhagic disorder for which the highest incidence
occurs in southeast Iran. The aim of this study was to assess molecular characteristics …

Confirmation of suspected congenital factor XIII (FXIII) deficiency still represents a diagnostic
challenge in the field of rare bleeding disorders. Because of the lack of awareness and …

Coagulation factor XIII (FXIII) acts as a fine fulcrum in blood plasma that maintains the
balance between bleeding and thrombosis by covalently crosslinking the pre-formed fibrin …

Mutational reports over the past two decades have accumulated an immense amount of
literature for inherited Factor XIII deficiency. However, the genotype and phenotype …

Factor XIII or" fibrin-stabilizing factor," is a transglutaminase circulates in the blood
circulation as a hetero tetramer with two catalytic A subunits and two carrier B subunits. This …

Factor XIII deficiency (FXIIID) is an extremely rare autosomal recessive disorder that has the
highest incidence in Iran. The FXIIID is primarily due to mutations in the FXIII-A gene, most of …

Congenital factor XIII (FXIII) deficiency is an extremely rare hemorrhagic disorder
characterized by a deficiency of FXIII and associated with a high rate of morbidity and …

Abstract Background Factor XIII (FXIII) deficiency is an extremely rare bleeding disorder,
which has the highest incidence in Sistan and Baluchistan Province in Iran, compared to its …