Antibiotic strategies for eradicating Pseudomonas aeruginosa in people with cystic fibrosis

SCL Hewer, S Smith, NJ Rowbotham… - Cochrane Database …, 2023 - cochranelibrary.com
Background Respiratory tract infections with Pseudomonas aeruginosa occur in most
people with cystic fibrosis (CF). Established chronic P aeruginosa infection is virtually …

Microbial epidemiology of the cystic fibrosis airways: past, present, and future

CS Thornton, MD Parkins - Seminars in Respiratory and …, 2023 - thieme-connect.com
Progressive obstructive lung disease secondary to chronic airway infection, coupled with
impaired host immunity, is the leading cause of morbidity and mortality in cystic fibrosis (CF) …

Reporting involvement activities with children and young people in paediatric research: a framework analysis

J Preston, G Biglino, V Harbottle, E Dalrymple… - Research Involvement …, 2023 - Springer
Background The active involvement of patients and the public in the design and delivery of
health research has been increasingly encouraged, if not enforced. Knowledge of how this …

Anti-Pseudomonas aeruginosa Vaccines and Therapies: An Assessment of Clinical Trials

MM Elmassry, JA Colmer-Hamood, J Kopel… - Microorganisms, 2023 - mdpi.com
Pseudomonas aeruginosa is a Gram-negative opportunistic pathogen that causes high
morbidity and mortality in cystic fibrosis (CF) and immunocompromised patients, including …

[HTML][HTML] Standards for the care of people with cystic fibrosis (CF); recognising and addressing CF health issues

PR Burgel, KW Southern, C Addy, A Battezzati… - Journal of Cystic …, 2024 - Elsevier
This is the third in a series of four papers updating the European Cystic Fibrosis Society
(ECFS) standards for the care of people with CF. This paper focuses on recognising and …

The vacuolar anti-Pseudomonal activity of neutrophil primary granule peptidyl-arginine deiminase enzymes

R Baird, A Yusuf, L Forde, K Pohl, K Kavanagh… - Frontiers in …, 2024 - frontiersin.org
The role of neutrophils in host defense involves several cell processes including
phagocytosis, degranulation of antimicrobial proteins, and the release of neutrophil …

[HTML][HTML] Modification Tadalafil and Macitentan tablets to aerosol

P Zarogoulidis, D Petridis, C Sardeli… - Frontiers in Bioscience …, 2022 - imrpress.com
Introduction: Aerosolised drugs have been approved for several diseases such as cystic
fibrosis and diabetes. Moreover; there are already drugs for pulmonary hypertension in …

Modeling Cystic Fibrosis Chronic Infection Using Engineered Mucus-like Hydrogels

CL O'Brien, S Spencer, N Jafari, AJ Huang… - ACS Biomaterials …, 2024 - ACS Publications
The airway mucus of patients with cystic fibrosis has altered properties, which create a
microenvironment primed for chronic infections that are difficult to treat. These complex …

[PDF][PDF] Standards for the care of people with cystic fibrosis (CF); recognising and addressing CF health issues

K Southern, A BATTEZZATI, C Berry, JP Bouchara… - 2024 - scientiasalut.gencat.cat
This is the third in a series of four papers updating the European Cystic Fibrosis Society
(ECFS) standards for the care of people with CF. This paper focuses on recognising and …

Research on Antimicrobial Utilization and Resistance in England 2021–22 (ESPAUR Report)

E Agnew, JV Robotham - Medical Sciences Forum, 2023 - mdpi.com
Medical Sciences Forum | Free Full-Text | Research on Antimicrobial Utilization and Resistance
in England 2021–22 (ESPAUR Report) Next Article in Journal National Antimicrobial …