Globally, tuberculosis (TB) has reemerged as a major cause of morbidity and mortality,
despite the use of the Mycobacterium bovis BCG vaccine and intensive attempts to improve …

The global tuberculosis (TB) control effort is focused on interrupting transmission of the
causative agent, Mycobacterium tuberculosis, through chemotherapeutic intervention in …

Background Mycobacterium tuberculosis (Mtb) becomes dormant and phenotypically drug
resistant when it encounters multiple stresses within the host. Inability of currently available …

Rhodococcus jostii RHA1 is a soil-residing actinomycete with many favorable metabolic
capabilities that make it an ideal candidate for the bioremediation of contaminated soils …

Mycobacteria exhibit two DNA damage response pathways: the LexA/RecA-dependent SOS
response and a LexA/RecA-independent pathway. Using a combination of transcriptomics …

Host redox dependent physiological responses play crucial roles in the determination of
mycobacterial infection process. Mtb explores oxygen rich lung microenvironments to initiate …

The intersection of tuberculosis (TB) with non-communicable diseases (NCDs), including
diabetes mellitus (DM), chronic lung disease (CLD), and cardiovascular disease (CVD), has …

Non-tuberculous mycobacteria (NTM) are ubiquitous environmental bacteria that can induce
pulmonary and non-pulmonary diseases in susceptible persons. It is reported that the …

Background As an intracellular human pathogen, Mycobacterium tuberculosis (Mtb) is facing
multiple stressful stimuli inside the macrophage and the granuloma. Understanding Mtb …

Pathogens frequently employ eukaryotic linear motif (ELM)-rich intrinsically disordered
proteins (IDPs) to perturb and hijack host cell networks for a productive infection …