Molecular and cellular mechanisms of liver fibrosis and its regression
T Kisseleva, D Brenner - Nature reviews Gastroenterology & hepatology, 2021 - nature.com
Chronic liver injury leads to liver inflammation and fibrosis, through which activated
myofibroblasts in the liver secrete extracellular matrix proteins that generate the fibrous scar …
myofibroblasts in the liver secrete extracellular matrix proteins that generate the fibrous scar …
[HTML][HTML] Nutraceutical approach to chronic osteoarthritis: from molecular research to clinical evidence
A Colletti, AFG Cicero - International journal of molecular sciences, 2021 - mdpi.com
Osteoarthritis (OA) is a degenerative inflammatory condition of the joint cartilage that
currently affects approximately 58 million adults in the world. It is characterized by pain …
currently affects approximately 58 million adults in the world. It is characterized by pain …
[HTML][HTML] Methylsulfonylmethane: applications and safety of a novel dietary supplement
M Butawan, RL Benjamin, RJ Bloomer - Nutrients, 2017 - mdpi.com
Methylsulfonylmethane (MSM) has become a popular dietary supplement used for a variety
of purposes, including its most common use as an anti-inflammatory agent. It has been well …
of purposes, including its most common use as an anti-inflammatory agent. It has been well …
[HTML][HTML] Organosulfur compounds: A review of their anti-inflammatory effects in human health
Phytonutrients are widely recognized for providing protective human health benefits. Among
the phytonutrients, epidemiological and experimental studies show that dietary organosulfur …
the phytonutrients, epidemiological and experimental studies show that dietary organosulfur …
Oxalate, inflammasome, and progression of kidney disease
T Ermer, KU Eckardt, PS Aronson… - Current opinion in …, 2016 - journals.lww.com
The findings reviewed in this article expand our understanding of the relevance of elevated
plasma oxalate levels leading to inflammasome activation. We propose that inhibiting …
plasma oxalate levels leading to inflammasome activation. We propose that inhibiting …
[HTML][HTML] Dietary thiols: A potential supporting strategy against oxidative stress in heart failure and muscular damage during sports activity
M Brancaccio, C Mennitti, A Cesaro, F Fimiani… - International Journal of …, 2020 - mdpi.com
Moderate exercise combined with proper nutrition are considered protective factors against
cardiovascular disease and musculoskeletal disorders. However, physical activity is known …
cardiovascular disease and musculoskeletal disorders. However, physical activity is known …
[HTML][HTML] Modulatory properties of food and nutraceutical components targeting NLRP3 inflammasome activation
M Spano, G Di Matteo, C Ingallina, D Ambroselli… - Nutrients, 2022 - mdpi.com
Inflammasomes are key intracellular multimeric proteins able to initiate the cellular
inflammatory signaling pathway. NLRP3 inflammasome represents one of the main protein …
inflammatory signaling pathway. NLRP3 inflammasome represents one of the main protein …
Isorhamnetin and hyperoside derived from water dropwort inhibits inflammasome activation
Abstract Background Water dropwort (Oenanthe javanica), an umbelliferous plant, has been
reported as hypolipidemic, antiplatelet, antitumor, or immune-stimulating agents and it has …
reported as hypolipidemic, antiplatelet, antitumor, or immune-stimulating agents and it has …
[HTML][HTML] Methylsulfonylmethane Improves Knee Quality of Life in Participants with Mild Knee Pain: A Randomized, Double-Blind, Placebo-Controlled Trial
A Toguchi, N Noguchi, T Kanno, A Yamada - Nutrients, 2023 - mdpi.com
Methylsulfonylmethane (MSM) is a food ingredient present in small amounts in many foods,
and its anti-inflammatory effects have been reported. We conducted a randomized, double …
and its anti-inflammatory effects have been reported. We conducted a randomized, double …
[HTML][HTML] Korean Red Ginseng, a regulator of NLRP3 inflammasome, in the COVID-19 pandemic
Abstract Coronavirus disease 2019 (COVID-19) exhibits various symptoms, ranging from
asymptomatic to severe pneumonia or death. The major features of patients in severe …
asymptomatic to severe pneumonia or death. The major features of patients in severe …