[HTML][HTML] Angiosarcoma: a review of diagnosis and current treatment

J Cao, J Wang, C He, M Fang - American journal of cancer …, 2019 - ncbi.nlm.nih.gov
Angiosarcoma is a highly malignancy of endothelial tumor and represents 1-2% of all soft
tissue sarcomas in humans. The aetiology of angiosarcoma is not clear but there are definite …

Therapeutic strategies of drug repositioning targeting autophagy to induce cancer cell death: from pathophysiology to treatment

GJ Yoshida - Journal of hematology & oncology, 2017 - Springer
Abstract The 2016 Nobel Prize in Physiology or Medicine was awarded to the researcher
that discovered autophagy, which is an evolutionally conserved catabolic process which …

Blockade of beta-adrenergic receptors reduces cancer growth and enhances the response to anti-CTLA4 therapy by modulating the tumor microenvironment

KY Fjæstad, AMA Rømer, V Goitea, AZ Johansen… - Oncogene, 2022 - nature.com
The development of immune checkpoint inhibitors (ICI) marks an important breakthrough of
cancer therapies in the past years. However, only a limited fraction of patients benefit from …

Cutaneous angiosarcoma: a current update

E Shustef, V Kazlouskaya, VG Prieto, D Ivan… - Journal of Clinical …, 2017 - jcp.bmj.com
Cutaneous angiosarcoma (cAS) is a rare malignant neoplasm with variable clinical
presentation. Although a distinct vascular tumour, cAS shares many overlapping …

Cutaneous angiosarcoma: update on biology and latest treatment

Y Ishida, A Otsuka, K Kabashima - Current opinion in oncology, 2018 - journals.lww.com
Cutaneous angiosarcoma: update on biology and latest treatme... : Current Opinion in
Oncology Cutaneous angiosarcoma: update on biology and latest treatment : Current Opinion …

Use of non-selective β-blockers is associated with decreased tumor proliferative indices in early stage breast cancer

A Montoya, CN Amaya, A Belmont, N Diab… - …, 2016 - pmc.ncbi.nlm.nih.gov
Previous studies suggest beta-adrenergic receptor (β-AR) antagonists (β-blockers)
decrease breast cancer progression, tumor metastasis, and patient mortality; however the …

β-blockers: Their new life from hypertension to cancer and migraine

C Fumagalli, N Maurizi, N Marchionni… - Pharmacological …, 2020 - Elsevier
The pharmacological class of β-blockers includes a plea of molecules with largely different
pharmacokinetic and pharmacodynamic characteristics with a protective effect that may …

Current and future directions for angiosarcoma therapy

V Florou, BA Wilky - Current treatment options in oncology, 2018 - Springer
Opinion statement Angiosarcomas are rare vascular neoplasms that are among the most
aggressive subtypes of soft tissue sarcomas. Surgical resection is often challenging even in …

[HTML][HTML] Beta-adrenergic receptors are expressed across diverse cancers

SL Rains, CN Amaya, BA Bryan - Oncoscience, 2017 - ncbi.nlm.nih.gov
Based largely on retrospective analyses and a handful of prospective case reports,
pharmacological inhibition of the beta adrenergic receptors using beta blockers has shown …

[HTML][HTML] Repurposing Drugs in Oncology (ReDO)—Propranolol as an anti-cancer agent

P Pantziarka, G Bouche, V Sukhatme… - …, 2016 - ncbi.nlm.nih.gov
Propranolol (PRO) is a well-known and widely used non-selective beta-adrenergic receptor
antagonist (beta-blocker), with a range of actions which are of interest in an oncological …