Clinical development of metal complexes as photosensitizers for photodynamic therapy of cancer
J Karges - Angewandte chemie international edition, 2022 - Wiley Online Library
Cancer has emerged over the last decades as one of the deadliest diseases in the world.
Among the most commonly used techniques (ie surgery, immunotherapy, radiotherapy or …
Among the most commonly used techniques (ie surgery, immunotherapy, radiotherapy or …
Luminescent and photofunctional transition metal complexes: From molecular design to diagnostic and therapeutic applications
There has been emerging interest in the exploitation of the photophysical and
photochemical properties of transition metal complexes for diagnostic and therapeutic …
photochemical properties of transition metal complexes for diagnostic and therapeutic …
Coupling probiotics with 2D CoCuMo‐LDH nanosheets as a tumor‐microenvironment‐responsive platform for precise NIR‐II photodynamic therapy
Y Yang, T Hu, Y Bian, F Meng, S Yu, H Li… - Advanced …, 2023 - Wiley Online Library
Photodynamic therapy (PDT) has become a promising cancer treatment approach with
superior advantages. However, it remains a grand challenge to develop tumor …
superior advantages. However, it remains a grand challenge to develop tumor …
Photodecaging of a mitochondria-localized iridium (III) endoperoxide complex for two-photon photoactivated therapy under hypoxia
Despite the clinical success of photodynamic therapy (PDT), the application of this medical
technique is intrinsically limited by the low oxygen concentrations found in cancer tumors …
technique is intrinsically limited by the low oxygen concentrations found in cancer tumors …
Cancer therapeutics based on diverse energy sources
Light-based phototherapy has been developed for cancer treatment owing to its non-
invasiveness and spatiotemporal control. Despite the unique merits of phototherapy, one …
invasiveness and spatiotemporal control. Despite the unique merits of phototherapy, one …
In response to precision medicine: Current subcellular targeting strategies for cancer therapy
Emerging as a potent anticancer treatment, subcellular targeted cancer therapy has drawn
increasing attention, bringing great opportunities for clinical application. Here, two targeting …
increasing attention, bringing great opportunities for clinical application. Here, two targeting …
A Biodegradable Iridium (III) Coordination Polymer for Enhanced Two‐Photon Photodynamic Therapy Using an Apoptosis–Ferroptosis Hybrid Pathway
The clinical application of photodynamic therapy is hindered by the high glutathione
concentration, poor cancer‐targeting properties, poor drug loading into delivery systems …
concentration, poor cancer‐targeting properties, poor drug loading into delivery systems …
Ferroptosis‐enhanced cancer immunity by a ferrocene‐appended iridium (III) Diphosphine complex
WJ Wang, YY Ling, YM Zhong, ZY Li… - Angewandte Chemie …, 2022 - Wiley Online Library
Ferroptosis is a programmed cell death pathway discovered in recent years, and ferroptosis‐
inducing agents have great potential as new antitumor candidates. Here, we report a IrIII …
inducing agents have great potential as new antitumor candidates. Here, we report a IrIII …
[HTML][HTML] Enzyme-triggered deep tumor penetration of a dual-drug nanomedicine enables an enhanced cancer combination therapy
Cancer cells could be eradicated by promoting generation of excessive intracellular reactive
oxygen species (ROS) via emerging nanomedicines. However, tumor heterogeneity and …
oxygen species (ROS) via emerging nanomedicines. However, tumor heterogeneity and …
[HTML][HTML] A highly potent ruthenium (II)-sonosensitizer and sonocatalyst for in vivo sonotherapy
C Liang, J Xie, S Luo, C Huang, Q Zhang… - Nature …, 2021 - nature.com
As a basic structure of most polypyridinal metal complexes,[Ru (bpy) 3] 2+, has the
advantages of simple structure, facile synthesis and high yield, which has great potential for …
advantages of simple structure, facile synthesis and high yield, which has great potential for …