Nitroalkanes and nitroalkenes have been always considered as convenient and readily
available intermediates in organic synthesis, including total synthesis of natural products. 1 …

Oxazines have brought much synthetic interest due to their extensive biological activities.
These are the important category of heterocycles, which may be formally derived from …

Aberrant activation of NF-κB is linked with the progression of human malignancies including
hepatocellular carcinoma (HCC), and blockade of NF-κB signaling could be a potential …

Hepatocellular carcinoma (HCC) is the fifth most common malignant tumor worldwide, and is
the third most common cause of cancer related death. Constitutive activation of NF-κB is the …

The anti-apoptotic protein Bcl-2 is a well-known and attractive therapeutic target for cancer.
In the present study the solution-phase T3P-DMSO mediated efficient synthesis of 2-amino …

Small molecules are being used to inhibit cyclin dependent kinase (CDK) enzymes in
cancer treatment. There is evidence that CDK is a drug-target for cancer therapy across …

In the present study, we used solution combustion synthesis-bismuth oxide (Bi 2 O 3) as
catalyst for the simple and efficient synthesis of 1, 2-oxazine based derivatives of 6-fluoro-3 …

Bismuth oxide was synthesized via simple, rapid and energy efficient solution combustion
synthesis (SCS) by employing sucrose as a fuel. This SCS-Bi2O3 was characterized by …

Constitutive activation of NF-κB is associated with proinflammatory diseases and
suppression of the NF-κB signaling pathway has been considered as an effective …

Metal-mediated C–H functionalization of cyclic N-oxides was exploited to access a series of
new difluoromethylated analogs of imidazolidinone-based PDE4 inhibitor CMPI in a …