Prognostic and therapeutic implications of minimal residual disease detection in acute myeloid leukemia
F Buccisano, L Maurillo, MI Del Principe… - Blood, The Journal …, 2012 - ashpublications.org
The choice of either induction or postremission therapy for adults with acute myeloid
leukemia is still largely based on the “one size fits all” principle. Moreover, pretreatment …
leukemia is still largely based on the “one size fits all” principle. Moreover, pretreatment …
Minimal residual disease in acute myeloid leukaemia
CS Hourigan, JE Karp - Nature reviews Clinical oncology, 2013 - nature.com
Technological advances in the laboratory have led to substantial improvements in clinical
decision making through the introduction of pretreatment prognostic risk stratification factors …
decision making through the introduction of pretreatment prognostic risk stratification factors …
Dendritic cell vaccination as postremission treatment to prevent or delay relapse in acute myeloid leukemia
S Anguille, AL Van de Velde, EL Smits… - Blood, The Journal …, 2017 - ashpublications.org
Relapse is a major problem in acute myeloid leukemia (AML) and adversely affects survival.
In this phase 2 study, we investigated the effect of vaccination with dendritic cells (DCs) …
In this phase 2 study, we investigated the effect of vaccination with dendritic cells (DCs) …
Real-Time Quantitative Polymerase Chain Reaction Detection of Minimal Residual Disease by Standardized WT1 Assay to Enhance Risk Stratification in Acute …
D Cilloni, A Renneville, F Hermitte, RK Hills… - Journal of Clinical …, 2009 - ascopubs.org
Purpose Risk stratification in acute myeloid leukemia (AML) is currently based on
pretreatment characteristics. It remains to be established whether relapse risk can be better …
pretreatment characteristics. It remains to be established whether relapse risk can be better …
Induction of complete and molecular remissions in acute myeloid leukemia by Wilms' tumor 1 antigen-targeted dendritic cell vaccination
VF Van Tendeloo, A Van de Velde… - Proceedings of the …, 2010 - National Acad Sciences
Active immunization using tumor antigen-loaded dendritic cells holds promise for the
adjuvant treatment of cancer to eradicate or control residual disease, but so far, most …
adjuvant treatment of cancer to eradicate or control residual disease, but so far, most …
Peripheral blood minimal residual disease may replace bone marrow minimal residual disease as an immunophenotypic biomarker for impending relapse in acute …
W Zeijlemaker, A Kelder, YJM Oussoren-Brockhoff… - Leukemia, 2016 - nature.com
As relapses are common in acute myeloid leukemia (AML), early relapse prediction is of
high importance. Although conventional minimal residual disease (MRD) measurement is …
high importance. Although conventional minimal residual disease (MRD) measurement is …
[HTML][HTML] MRD assessed by WT1 and NPM1 transcript levels identifies distinct outcomes in AML patients and is influenced by gemtuzumab ozogamicin
J Lambert, J Lambert, O Nibourel, C Pautas… - Oncotarget, 2014 - ncbi.nlm.nih.gov
MRD assessed by WT1 and NPM1 transcript levels identifies distinct outcomes in AML patients
and is influenced by gemtuzumab ozogamicin - PMC Back to Top Skip to main content NIH …
and is influenced by gemtuzumab ozogamicin - PMC Back to Top Skip to main content NIH …
Monitoring minimal residual disease in acute myeloid leukaemia: a review of the current evolving strategies
HB Ommen - Therapeutic advances in hematology, 2016 - journals.sagepub.com
Several disease-monitoring techniques are available for the physician treating acute
myeloid leukaemia (AML). Besides immunohistochemistry assisted light microscopy, the …
myeloid leukaemia (AML). Besides immunohistochemistry assisted light microscopy, the …
Monitoring of WT1 expression in PB and CD34+ donor chimerism of BM predicts early relapse in AML and MDS patients after hematopoietic cell transplantation with …
T Lange, M Hubmann, R Burkhardt, GN Franke… - Leukemia, 2011 - nature.com
Relapse of malignant disease remains the major complication in patients with acute myeloid
leukemia (AML) or myelodysplastic syndrome (MDS) after hematopoietic cell transplantation …
leukemia (AML) or myelodysplastic syndrome (MDS) after hematopoietic cell transplantation …
Bone marrow WT1 levels at diagnosis, post-induction and post-intensification in adult de novo AML
JF Nomdedéu, M Hoyos, M Carricondo, E Bussaglia… - Leukemia, 2013 - nature.com
We retrospectively assessed whether normalized bone marrow WT1 levels could be used
for risk stratification in a consecutive series of 584 acute myeloid leukemia (AML) patients. A …
for risk stratification in a consecutive series of 584 acute myeloid leukemia (AML) patients. A …