Bladder cancer

L Dyrskjøt, DE Hansel, JA Efstathiou… - Nature Reviews …, 2023 - nature.com
Bladder cancer is a global health issue with sex differences in incidence and prognosis.
Bladder cancer has distinct molecular subtypes with multiple pathogenic pathways …

Circulating tumour DNA—looking beyond the blood

A Tivey, M Church, D Rothwell, C Dive… - Nature reviews clinical …, 2022 - nature.com
Over the past decade, various liquid biopsy techniques have emerged as viable alternatives
to the analysis of traditional tissue biopsy samples. Such surrogate 'biopsies' offer numerous …

Circulating tumor DNA analysis guiding adjuvant therapy in stage II colon cancer

J Tie, JD Cohen, K Lahouel, SN Lo… - … England Journal of …, 2022 - Mass Medical Soc
Background The role of adjuvant chemotherapy in stage II colon cancer continues to be
debated. The presence of circulating tumor DNA (ctDNA) after surgery predicts very poor …

[HTML][HTML] ESMO recommendations on the use of circulating tumour DNA assays for patients with cancer: a report from the ESMO Precision Medicine Working Group

J Pascual, G Attard, FC Bidard, G Curigliano… - Annals of …, 2022 - Elsevier
Circulating tumour DNA (ctDNA) assays conducted on plasma are rapidly developing a
strong evidence base for use in patients with cancer. The European Society for Medical …

ctDNA guiding adjuvant immunotherapy in urothelial carcinoma

T Powles, ZJ Assaf, N Davarpanah, R Banchereau… - Nature, 2021 - nature.com
Minimally invasive approaches to detect residual disease after surgery are needed to
identify patients with cancer who are at risk for metastatic relapse. Circulating tumour DNA …

Advances in bladder cancer biology and therapy

L Tran, JF Xiao, N Agarwal, JE Duex… - Nature Reviews …, 2021 - nature.com
The field of research in bladder cancer has seen significant advances in recent years. Next-
generation sequencing has identified the genes most mutated in bladder cancer. This …

Bladder cancer: a review

AT Lenis, PM Lec, K Chamie - Jama, 2020 - jamanetwork.com
Importance Bladder cancer is a common malignancy in women and is the fourth most
common malignancy in men. Bladder cancer ranges from unaggressive and usually …

Detecting liquid remnants of solid tumors: circulating tumor DNA minimal residual disease

EJ Moding, BY Nabet, AA Alizadeh, M Diehn - Cancer discovery, 2021 - AACR
Growing evidence demonstrates that circulating tumor DNA (ctDNA) minimal residual
disease (MRD) following treatment for solid tumors predicts relapse. These results suggest …

Personalized circulating tumor DNA analysis as a predictive biomarker in solid tumor patients treated with pembrolizumab

SV Bratman, SYC Yang, MAJ Iafolla, Z Liu, AR Hansen… - Nature Cancer, 2020 - nature.com
Immune checkpoint blockade (ICB) provides clinical benefit to a subset of patients with
cancer. However, existing biomarkers do not reliably predict treatment response across …

Clinical relevance of blood-based ctDNA analysis: mutation detection and beyond

L Keller, Y Belloum, H Wikman, K Pantel - British journal of cancer, 2021 - nature.com
Cell-free DNA (cfDNA) derived from tumours is present in the plasma of cancer patients. The
majority of currently available studies on the use of this circulating tumour DNA (ctDNA) deal …