Tumor cell plasticity in targeted therapy-induced resistance: mechanisms and new strategies

ZD Shi, K Pang, ZX Wu, Y Dong, L Hao… - … and Targeted Therapy, 2023 - nature.com
Despite the success of targeted therapies in cancer treatment, therapy-induced resistance
remains a major obstacle to a complete cure. Tumor cells evade treatments and relapse via …

Platelet-derived drug delivery systems: pioneering treatment for cancer, cardiovascular diseases, infectious diseases, and beyond

Y Zhu, L Xu, Y Kang, Q Cheng, Y He, X Ji - Biomaterials, 2024 - Elsevier
Platelets play a critical role as circulating cells in the human body and contribute to essential
physiological processes such as blood clotting, hemostasis, vascular repair, and thrombus …

Bioengineered bacterial membrane vesicles with multifunctional nanoparticles as a versatile platform for cancer immunotherapy

XZ Liu, ZJ Wen, YM Li, WR Sun, XQ Hu… - … Applied Materials & …, 2023 - ACS Publications
Inducing immunogenic cell death (ICD) is a critical strategy for enhancing cancer
immunotherapy. However, inefficient and risky ICD inducers along with a tumor hypoxia …

Cell‐based drug delivery systems participate in the cancer immunity cycle for improved cancer immunotherapy

X Fan, K Wang, Q Lu, Y Lu, J Sun - Small, 2023 - Wiley Online Library
Immunotherapy aims to activate the cancer patient's immune system for cancer therapy. The
whole process of the immune system against cancer referred to as the “cancer immunity …

Biomembrane nanostructures: Multifunctional platform to enhance tumor chemoimmunotherapy via effective drug delivery

X Jiang, L Wu, M Zhang, T Zhang, C Chen, Y Wu… - Journal of Controlled …, 2023 - Elsevier
Chemotherapeutic drugs have been found to activate the immune response against tumors
by inducing immunogenic cell death, in addition to their direct cytotoxic effects toward …

The role of tumor-platelet interplay and micro tumor thrombi during hematogenous tumor metastasis

Q Shi, T Ji, X Tang, W Guo - Cellular Oncology, 2023 - Springer
Background In addition to their pivotal roles in coagulation and thrombosis, platelets are
crucial in tumor progression, with plenty of clinical and experimental data demonstrating that …

Nanobiomimetic medicine

M Chang, C Dong, H Huang, L Ding… - Advanced Functional …, 2022 - Wiley Online Library
The application of nanotechnology in medicine aims at developing the precise theranostics
of diseases by leveraging the extraordinary effects of engineered nanomedicines …

Revolutionizing cancer treatment: The power of cell-based drug delivery systems

Q Lu, T Liu, Z Han, J Zhao, X Fan, H Wang… - Journal of Controlled …, 2023 - Elsevier
Intravenous administration of drugs is a widely used cancer therapy approach. However, the
efficacy of these drugs is often hindered by various biological barriers, including circulation …

Cell-based intelligent micro/nanorobots for precise regulation and active biotherapy

G Huang, T Yin, B Zhang, A Ma, T Kang, Y He, Y Long… - Matter, 2023 - cell.com
Precision medicine has shown great promise in the field of individual biomedicine and its
clinical application. However, accurate and efficient treatment remains challenging due to …

Artificial nanoplatelet regulation of tumor immune microenvironment to inhibit post-surgical tumor recurrence and lung metastasis

K Zhang, Y Long, Z Ma, S Li, Y Zhao, H Han - Materials Today, 2023 - Elsevier
Tumor recurrence and metastasis are important causes of death in breast cancer patients
after surgery. However, the nanomedicines are often difficult to accumulate and retain in …