The echocardiographic ratio tricuspid annular plane systolic excursion/pulmonary arterial systolic pressure predicts short-term adverse outcomes in acute pulmonary …

MD Lyhne, C Kabrhel, N Giordano… - European Heart …, 2021 - academic.oup.com
Aims Right ventricular (RV) failure causes death from acute pulmonary embolism (PE), due
to a mismatch between RV systolic function and increased RV afterload. We hypothesized …

Right ventricular-pulmonary artery coupling for prognostication in acute pulmonary embolism

MD Lyhne, B Bikdeli, D Jiménez… - … Heart Journal: Acute …, 2024 - academic.oup.com
Aims Acute pulmonary embolism (PE) increases pulmonary pressure and impair right
ventricular (RV) function. Echocardiographic investigation can quantify this mismatch as the …

The hemodynamic interplay between pulmonary ischemia-reperfusion injury and right ventricular function in lung transplantation: a translational porcine model

M Orlitová, T Verbelen, AE Frick… - … of Physiology-Lung …, 2023 - journals.physiology.org
Lung transplantation (LTx) is a challenging procedure. Following the process of ischemia-
reperfusion injury, the transplanted pulmonary graft might become severely damaged …

Levosimendan, milrinone, and dobutamine in experimental acute pulmonary embolism

MD Lyhne, SJ Dragsbaek, JV Hansen… - Pulmonary …, 2021 - journals.sagepub.com
Acute pulmonary embolism is a frequent condition in emergency medicine and potentially
fatal. Cause of death is right ventricular failure due to increased right ventricular afterload …

Oxygen therapy lowers right ventricular afterload in experimental acute pulmonary embolism

MD Lyhne, JV Hansen, SJ Dragsbaek… - Critical Care …, 2021 - journals.lww.com
OBJECTIVES: To investigate if oxygen could unload the right ventricle and improve right
ventricle function in a porcine model mimicking intermediate-high risk acute pulmonary …

Right‐to‐left ventricular ratio is higher in systole than diastole in patients with acute pulmonary embolism

MD Lyhne, DM Dudzinski, A Andersen… - …, 2023 - Wiley Online Library
Objectives In acute pulmonary embolism (PE), the right ventricle (RV) may dilate
compromising left ventricular (LV) size, thereby increasing RV/LV ratio. End‐diastolic RV/LV …

Management Strategies for Acute Pulmonary Embolism in the Intensive Care Unit

WC McGuire, L Sullivan, MF Odish, B Desai, TA Morris… - Chest, 2024 - Elsevier
Abstract Topic Importance Acute pulmonary embolism (PE) is a common disease
encountered by pulmonologists, cardiologists, and critical care physicians throughout the …

Closed chest biventricular pressure-volume loop recordings with admittance catheters in a porcine model

MD Lyhne, JG Schultz, SJ Dragsbaek… - JoVE (Journal of …, 2021 - jove.com
Pressure-volume (PV) loop recording enables the state-of-the-art investigation of load-
independent variables of ventricular performance. Uni-ventricular evaluation is often …

Impact of sternotomy and pericardiotomy on cardiopulmonary haemodynamics in a large animal model

ME Kirk, VT Merit, N Moeslund… - Experimental …, 2023 - Wiley Online Library
Animal models of cardiovascular disease are often evaluated by invasive instrumentation for
phenotyping. As no consensus exists, both open‐and closed‐chest approaches are used …

Inferior vena cava contrast reflux grade is associated with a reduced cardiac index in acute pulmonary embolism

E Yuriditsky, RS Zhang, P Zhang, JM Horowitz… - Thrombosis …, 2024 - Elsevier
Abstract Background and Aims Patients with intermediate-risk pulmonary embolism (PE)
commonly present with a significantly reduced cardiac index (CI). However, the identification …